Drug Combo May Help Lower Danger After Mini-Stroke

The American Stroke Association reports that more than one-third of U.S. adults have had a transient ischemic attack/mini-stroke.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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ConclusionsOur results provide indirect evidence that the epidemiological profile of stroke is changing based on the increase in hospitalisation rates in young adults.ResumenIntroducciónLa incidencia del ictus en nuestro medio ha sido evaluada en diferentes estudios con amplia variabilidad y no comparables. Tampoco hay estudios que analicen los cambios epidemiológicos en pacientes más jóvenes.MétodoEstudio retrospectivo observacional. Conjunto Mínimo Básico de Datos. Se seleccionó a todos los pacientes mayores de 19 años hospitalizados por ictus (códigos...
Source: Neurologia - Category: Neurology Source Type: research
Conclusions Hypotension is a potentially modifiable risk factor for perioperative stroke. The study ’s findings suggest that mean arterial pressure may be an important intraoperative therapeutic hemodynamic target to reduce the incidence of stroke in patients undergoing cardiopulmonary bypass.
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Condition:   Ischemic Stroke Interventions:   Other: head-down position treatment;   Other: Conventional Rehabilitation Sponsor:   General Hospital of Shenyang Military Region Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Ischemic Stroke;   Chronic Stroke;   Hemiparesis;   Arm Paralysis Interventions:   Combination Product: CTX0E03 Drug Product and delivery device;   Drug: Placebo Sponsor:   ReNeuron Limited Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Wang DS, Yin RX, Li KG, Lu L, Su Y, Yan RQ Abstract The association between the mevalonate kinase gene (MVK) single nucleotide polymorphism (SNP) and serum lipid levels has been detected in several previous genome-wide association studies, but the results are inconsistent. In addition, it is still unclear whether the loci indentified exert the similar effect on the susceptibility of coronary heart disease (CHD) or ischemic stroke (IS). Therefore, the present study was undertaken to detect the association between the MVK rs2287218 SNP and serum lipid levels, the susceptibility of CHD and IS in a Southern Ch...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
ConclusionsIn patients with T2D and persistent microalbuminuria, u-KIM-1, but not u-NGAL, was an independent risk factor for decline in eGFR, CVE and all-cause mortality, and contributed significant discrimination for all-cause mortality, beyond traditional risk factors.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
Acute ischemic thrombosis in patients who have undergone neurosurgical procedures is a leading cause of mortality and long-term disability. Endovascular therapy has become an important treatment modality for acute ischemic thrombosis in these patients. Noninvasive imaging has dramatically changed the understanding of cerebral blood flow and the concepts of cerebrovascular reserve and salvageable penumbra. Increasingly, reliance on perfusion imaging to discern tissue viability and potential outcomes has become standard of care. With the advent of recent acute ischemic stroke trials, therapy for occlusive cerebrovascular dis...
Source: Neurosurgery Clinics of North America - Category: Neurosurgery Authors: Source Type: research
ConclusionsCerebrovascular events may be the first manifestation of neurosarcoidosis, and have a prognosis impact in such patients, leading to death and permanent neurological impairment.
Source: Journal of Neurology - Category: Neurology Source Type: research
AbstractFree-floating thrombi of the common carotid artery (CCA) are a very rare cause of ischemic stroke. To date, only a few reports have been described in the academic literature. Revascularization is indicated due to the risk of thromboembolic disease and hemodynamic-related stroke syndromes. Medical treatment typically includes anticoagulation and, in some circumstances, open surgical thrombectomy is an additional option. Although rarely described in the literature, endovascular thrombectomy is a viable treatment alternative in these patients.
Source: Neuroradiology - Category: Radiology Source Type: research
Conclusion: No significant difference was observed by comparing patients and controls. In this study, no association was found between the presence of the evaluated polymorphisms and the occurrence of thrombotic events.RESUMO Introdu ção: A trombose arterial é considerada uma doença multifatorial, resultante da interação de fatores de risco genéticos e adquiridos. Objetivos: O objetivo deste estudo foi investigar a presença dos polimorfismos nos genes do inibidor da ativação do plasminogênio tipo 1 (PAI-1) e da apoli poproteína E (ApoE), bem...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
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