New, Faster, Rabies Test Could Save Lives

Rabies is fatal if not treated early. With a better test, people exposed to potentially rabid animals could avoid the weeks-long series of shots now given to prevent the disease.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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ConclusionsThe FuG-E (P440E) pseudotype provides a powerful tool to investigate neural circuit mechanisms underlying various brain functions and for gene therapy trials of neurological and neurodegenerative diseases.
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research
Condition:   Rabies Interventions:   Biological: Rabipur®;   Biological: Rabies mRNA vaccine CV7202 Dose level 1;   Biological: Rabies mRNA vaccine CV7202 Dose level 2;   Biological: Rabies mRNA vaccine CV7202 Dose level 3;   Biological: Rabies mRNA vaccine CV7202 Dose level 4;   Biological: Rabies mRNA vaccine CV7202 Dose l evel 5;   Biological: Rabies mRNA vaccine CV7202 Dose level 6 Sponsor:   CureVac AG Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Clinical Case Reports, EarlyView.
Source: Clinical Case Reports - Category: General Medicine Authors: Source Type: research
According to 2010-2014 World Health Organization (WHO) research, dog-transmitted human rabies was present or suspected in 150 countries and territories worldwide. Domestic dogs were the most common reservoir of the rabies virus in these countries, and more than 99% of human deaths were caused by dog-transmitted rabies. Rabies is 100% preventable in dogs with appropriate administration of vaccines.Virus neutralization assays are essential for assessing vaccine efficacy. Current methods to detect rabies-specific neutralizing antibodies involve skilled personnel using a traditional 8-well slide and manually reading a microsco...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
A unit of China's vaccine maker Changsheng Bio-technology Co Ltd has been hit with penalties totaling 9.1 billion yuan ($1.32 billion) after it was embroiled in a scandal over falsifying data for a rabies vaccine.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/17/2018 8:23:00 AM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Conclusion: Children are innocent and behavior of dogs are unpredictable hence they become victims of the dog attacks. Educating children on safe animal behavior can prove vital in reducing gruesome maxillofacial injuries resulting from dog attacks.
Source: Journal of Indian Society of Pedodontics and Preventive Dentistry - Category: Dentistry Authors: Source Type: research
mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/17/2018 8:23:00 AM
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
We read the recent case report by Villamar et al.1 and have concerns about the conclusion that the patient died of rabies. First, it would be useful to know when the case occurred and whether there was any history of an animal exposure. This is basic historical information that should be sought in a case of suspected rabies and could be obtained postmortem if the diagnosis was not considered during life. Second, the initial 1-month history of personality change and declining academic performance and the 2-week gap between the initial seizure and the status epilepticus are incompatible with rabies encephalitis, which i...
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: The Nerve! Readers Speak Source Type: research
We thank Drs. Jackson and Del Bigio for their comments on our case report.1 The authors argue that there were insufficient data to support a diagnosis of rabies encephalitis, but do not offer an alternative, more cohesive explanation for the reported findings. The history of a fulminant and fatal course of new-onset refractory status epilepticus would be consistent, in our viewpoint, with what they believe does not qualify for a "rapid progressive neurologic deterioration." It is certainly possible that the nonspecific symptoms of personality change and declining academics in the preceding month were unrelated.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: The Nerve! Readers Speak Source Type: research
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