TRIM22 knockdown suppresses chronic myeloid leukemia via inhibiting PI3K/Akt/mTOR signaling pathway.

In conclusion, loss of TRIM22 suppresses the progression and invasion of CML through regulation of PI3K/Akt/mTOR pathway, suggesting that TRIM22 might be as a potential target for the treatment strategy of CML.
PMID: 29762880 [PubMed - as supplied by publisher]

Source: Cell Biology International - May 15, 2018 Category: Cytology Authors: Li L, Qi Y, Ma X, Xiong G, Wang L, Bao C Tags: Cell Biol Int Source Type: research