Multiparametric Magnetic Resonance Imaging Is an Independent Predictor of Salvage Radiotherapy Outcomes After Radical Prostatectomy

Conclusions Pre-sXRT mpMRI improves clinicopathologic variables to estimate sXRT success, particularly in the early sXRT setting. Patient summary Men who have biochemically recurrent prostate cancer after radical prostatectomy often receive salvage radiotherapy. In our study, multiparametric pelvic magnetic resonance imaging prior to salvage radiotherapy was a significant predictor of prostate-specific antigen failure and metastasis after radiotherapy. Multiparametric magnetic resonance imaging (mpMRI) before salvage radiotherapy is a valuable prognostic adjunct to current clinicopathologic variables. Negative mpMRI was an independent risk factor for prostate-specific antigen (PSA) recurrence and metastasis for patients undergoing salvage radiotherapy with a PSA of <0.5ng/ml.
Source: European Urology - Category: Urology & Nephrology Source Type: research