Virulence determinants, biofilm production and antimicrobial susceptibility in Staphylococcus aureus causing device-associated infections in a Tunisian hospital

Staphylococcus aureus is a major human pathogen that causes a wide range of clinical infections. The increased use of indwelling medical devices has had considerable impact on the role of S. aureus in clinical medicine [1]. In fact, S. aureus strains causing device related infections (DRI) displayed the ability to form surface-attached communities of cells called biofilms on polymeric surfaces facilitating their persistence in the host, evading host defences mechanisms and allowing bacterial survival at high antimicrobial concentrations [2]
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research