Phenotypic and genetic resistance traits in Pseudomonas aeruginosa strains infecting cystic fibrosis patients: a French cohort study

Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium of the aquatic environment and a major opportunistic human pathogen [1]. This organism is responsible for nosocomial infections, which may be life-threatening especially in immunosuppressed patients [1]. It is also the leading cause of morbidity and mortality in cystic fibrosis (CF) patients, causing chronic respiratory tract infections with acute exacerbations, which progressively impair the respiratory functions [1]. This bacterium is naturally resistant to many antibiotics [2], and can develop multi-drug resistance that represents a therapeutic challenge [3].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research