Imaging mycobacterial growth and division with a fluorogenic probe [Chemistry]

Control and manipulation of bacterial populations requires an understanding of the factors that govern growth, division, and antibiotic action. Fluorescent and chemically reactive small molecule probes of cell envelope components can visualize these processes and advance our knowledge of cell envelope biosynthesis (e.g., peptidoglycan production). Still, fundamental gaps remain in...

Source: Proceedings of the National Academy of Sciences - May 15, 2018 Category: Science Authors: Heather L. Hodges, Robert A. Brown, John A. Crooks, Douglas B. Weibel, Laura L. Kiessling Tags: Biological Sciences Source Type: research