AMPA-ergic regulation of amyloid- β levels in an Alzheimer’s disease mouse model

Extracellular aggregation of the amyloid- β (Aβ) peptide into toxic multimers is a key event in Alzheimer’s disease (AD) pathogenesis. Aβ aggregation is concentration-dependent, with higher concentrations of Aβ...

Source: Molecular Neurodegeneration - May 15, 2018 Category: Neurology Authors: Jane C. Hettinger, Hyo Lee, Guojun Bu, David M. Holtzman and John R. Cirrito Tags: Research article Source Type: research