Habitual aerobic exercise, gene APOA5 named rs662799 SNP and response of blood lipid and lipoprotein phenotypes among older Chinese adult.

CONCLUSIONS: Excess risk for low HDL-C and hyperlipidemia was associated with rs662799 genotype alleles of APOA5 SNPs in older Chinese adults. Interaction of gene-HAE and HAE levels may induce different responses of blood lipids and lipoprotein phenotypes. HAE levels have less influence on TG changes in the AA carriers; however, high HAE levels appeared to greatly impact TG responses in the AG + GG carriers.
PMID: 29758349 [PubMed - as supplied by publisher]

Source: Experimental Gerontology - May 11, 2018 Category: Geriatrics Authors: Liu X, Huang G, Niu Z, Wei Y, Wang R Tags: Exp Gerontol Source Type: research