Robert Chapkin on Relationships Between the Gut Microbiome, Diet, and Colorectal Cancer
In this Q&A, we discuss the research into the relationships between gut microbiota, diet, and colorectal cancer.
Ziwei Zhou, Jiewen Chen, Herui Yao, Hai Hu
Adding contrast-enhanced ultrasound to conventional ultrasound improves diagnostic...Read more on AuntMinnie.comRelated Reading: Drop ultrasound contrast agent warning, society says Contrast US tops CT, MRI for classifying kidney tumors Contrast ultrasound is effective for liver, kidney lesions Contrast ultrasound identifies early cervical cancer Can CEUS differentiate between IBD and colon cancer?
Cancer Medicine, EarlyView.
Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers, Published online: 15 October 2018; doi:10.1038/s41416-018-0249-9Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers
An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancerAn IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer, Published online: 15 October 2018; doi:10.1038/s41416-018-0259-7An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer
ConclusionNotre étude a mis l’accent sur la fréquence très importante des dysfonctions sexuelles chez les patients atteints de cancer colorectal traité. Une meilleure connaissance de ces facteurs prédictifs de DE dans cette population devrait permettre de repérer et prendre en charge de façon adaptée les troubles sexuels de ces patients.SummaryBackgroundAlthough the effect of colorectal cancer treatment on sexual function has been well established, the impact of psychosocial variables, such as depression and social support, has been neglected. We aimed in this s...
Conclusion: LN metastasis is a significant prognostic factor in stage IV by hematogenous metastasis, too. N stage progression accumulates pathologically poor prognostic factors. However, the effect on survival of each N stage progression differs depending on curative resection or not of the hematogenous metastases. PMID: 30310803 [PubMed]
This study suggests that exocrine glands can be induced from pluripotent stem cells for organ replacement regenerative therapy. Replacement of Aged Microglia Partially Reverses Cognitive Decline in Mice https://www.fightaging.org/archives/2018/10/replacement-of-aged-microglia-partially-reverses-cognitive-decline-in-mice/ Researchers here report on a compelling demonstration that shows the degree to which dysfunctional microglia contribute to age-related neurodegeneration. The scientists use a pharmacological approach to greatly deplete the microglial population and then allow it to recover naturally. The...
Publication date: Available online 13 October 2018Source: Journal of Geriatric OncologyAuthor(s): Marlid Cruz-Ramos, Laura del Puerto-Nevado, Binbin Zheng, Rafael López-Bajo, Arancha Cebrian, María Rodríguez-Remirez, Laura García-García, Sonia Solanes-Casado, Jesús García-FoncillasAbstractAging is associated with a higher risk of cancer,>70% of cancer-related deaths occur in aged patients; however, this population is underrepresented in clinical trials, therefore, clinical information regarding this age group is rather limited.ObjectivesNeutrophil-to lymphocyte ratio (NLR...
ConclusionNon-Western immigrants have more than three times the risk of submitting an ineligible faeces sample for colorectal cancer screening than native Danes. Translation of invitation, information leaflet, and manual into other languages or targeted information for subgroups may help decrease the risk.