Clinicopathologic Significance of LAIR-1 Expression in Hepatocellular Carcinoma

Worldwide, hepatocellular carcinoma (HCC) currently represents the fifth most commonly occurring solid tumor mass and the third leading cause of cancer-related deaths [1, 2]. In spite of remarkable progress in the treatment and understanding of HCC, the molecular mechanisms underlying HCC carcinogenesis remain to be elucidated [3, 4]. Most HCC patients are considered incurable as a result of extensive heterogeneity in clinical presentations and tumor biology, which complicates the classification and procedures for therapy [5, 6].

Source: Current Problems in Cancer - April 28, 2018 Category: Cancer & Oncology Authors: Xiaojie Wu, Leyan Zhang, Jiadi Zhou, Luying Liu, Qiang Fu, Aili Fu, Xiaoying Feng, Rui Xin, Hongrui Liu, Yong Gao, Jiangnan Xue Source Type: research