Skin Graft Fixation Using Hydrofiber (Aquacel® Extra)

Conclusions The use of hydrofiber for skin graft fixation was effective and technically very simple. Splints were not required with this method, decreasing the medical waste created and increasing patient comfort. We suggest that this is an excellent alternative for skin graft fixation while at the same time decreasing our carbon footprint as surgeons.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Burn Surgery and Research Source Type: research

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Argentum Medical’s antimicrobial dressings received an extra bit of validation after strong results from recent lab findings. The Geneva, IL-based company’s Silverlon antimicrobial dressing was found to effectively kill Candida Auris (C. Auris), the emerging “superbug” causing invasive, potentially fatal human infection in more than 30 countries, including the U.S. Argentum Medical commissioned Microbiological Consultants, an independent FDA-registered pharmaceutical testing laboratory, to establish if its metallic wound dressings can destroy C. Auris ...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Source Type: news
Since the 1980s, deep and extensive skin wounds and burns are treated with autologous Split-Thickness Skin Grafts, or Cultured Epidermal Autografts (CEAs) when donor sites are limited. However, the clinical use of CEAs often remains unsatisfactory due to poor engraftment rates, altered wound healing and reduced skin functionality.In the past few decades, Mesenchymal Stromal Cells (MSCs) have raised much attention due to their anti-inflammatory, pro-trophic and pro-remodeling capacities. More specifically, gingival MSCs have been shown to possess enhanced wound healing properties compared to other tissue sources.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
STUDY OBJECTIVE: First-aid guidelines recommend the administration of cool running water in the early management of thermal injury. Our objective is to analyze the associations between first aid and skin-grafting requirements in children with burns. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
The aim of exenteration reconstruction is to stabilize the postsurgical wound bed to promote expeditious healing particularly in patients who are undergoing adjuvant radiation and/or chemotherapy. Porcine urinary bladder matrix has previously been used successfully as a wound-healing scaffold in treatment of burns and in acute, chronic, and surgical wounds, but the use of these products has not previously been reported in the exenterated orbit. The authors present a case of the novel use of porcine urinary bladder matrix in a pediatric patient who underwent exenteration for recurrent embryonal rhabdomyosarcoma, subsequent ...
Source: Ophthalmic Plastic and Reconstructive Surgery - Category: Opthalmology Tags: Case Reports Source Type: research
ConclusionBurn severity and clinical outcomes improved with the administration of cool running water. Adequate first aid must be prioritized by out-of-hospital and emergency medical services in the preliminary management of pediatric burns.
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
Thermal injury leads to loss of the regenerative capacity of the skin and scarring becomes a significant risk, due to the inability to emulate normal skin architecture and adnexal structures. Mesenchymal stem cells (MSC) have been used in a variety of clinical applications to repair and regenerate damaged tissue. MSC ’s can stimulate cellular processes such as fibroblast proliferation, migration, and endothelial angiogenesis, as well as modulate the host’s immune response to favor more optimal wound healing.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
A 38-year-old man was referred to the dermatology department because of a delayed healing of burn injuries. The patient was recently discharged from the hospital for electrical and thermal burn injuries on the face and body for which he underwent skin grafts. However, the wounds would not completely heal, even with treatment of a herpesvirus superinfection, multiple antibiotics treatments based on various bacterial cultures that were sampled from the beginning and adequate wound care. He only had a partial response to a combination of clobetasol and fusidic acid months after his skin grafts.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
AbstractPatients with extensive and deep burns who do not have enough donor sites for autologous skin grafts require alternative treatment methods. Tissue engineering is a useful tool to solve this problem. The aim of this study was to find the optimal method for the production of a biovital skin substitute based on acellular dermal matrix (ADM) and in vitro cultured fibroblasts and keratinocytes. In this work, nine methods of ADM production were assessed. The proposed methods are based on the use of the following enzymes: Dispase II, collagenase I/ethylenediaminetetraacetic acid (EDTA), collagenase II/EDTA, and mechanical...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - Category: Materials Science Authors: Tags: ORIGINAL RESEARCH REPORT Source Type: research
Publication date: Available online 14 August 2019Source: BurnsAuthor(s): Stefanie Nickl, Alexandra Fochtmann-Frana, Jakob Nedomansky, Wolfgang Hitzl, Lars-Peter Kamolz, Werner HaslikAbstractIntroductionAir-fluidized therapy (AFT) has long been used in the treatment of severe burns. In patients with extensive burns involving the posterior trunk, we aim to keep affected posterior areas dry and to postpone their treatment, initially applying available split-thickness skin grafts in functionally more important regions. We retrospectively assessed the impact of AFT on the survival of patients treated in the burn intensive care ...
Source: Burns - Category: Dermatology Source Type: research
We describe an isolation method, characterize a population, and investigate its potential for cell banking and thus suitability as a potential product for cell grafting therapies. Our results show hFDF and a bone marrow-derived mesenchymal stem cell (BM-MSC) line shared identification markers and in vitro multilineage differentiation potential into osteogenic, chondrogenic, and adipogenic lineages. The hFDF population exhibited similar cell characteristics as BM-MSC while producing lower pro-inflammatory cytokine IL-6 levels and higher levels of the wound healing factor hepatocyte growth factor. We demonstrate in vitro dif...
Source: Cell Transplantation - Category: Cytology Authors: Tags: Cell Transplant Source Type: research
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