Manual dexterity and brain structure in patients with schizophrenia: A whole-brain magnetic resonance imaging study

Patients with schizophrenia exhibit impairments in a variety of cognitive functions, including fine motor (e.g., manual) dexterity (Ayesa-Arriola et  al., 2013; Gonzalez-Blanch et al., 2007; Heinrichs and Zakzanis, 1998; Midorikawa et al., 2008; Sponheim et al., 2010). The Purdue Pegboard Test (PPT) is a bimanual coordination task that can be used to assess psychomotor abilities (i.e., motor speed and coordination) in subjects, such as patie nts with schizophrenia (Lee et al., 2013). PPT scores are consistently lower in patients with schizophrenia compared with healthy controls (Docx et al., 2013; Fuller and Jahanshahi, 1999; Galderisi et al., 2009).

Source: Psychiatry Research: Neuroimaging - April 14, 2018 Category: Psychiatry Authors: Shinsuke Hidese, Miho Ota, Daimei Sasayama, Junko Matsuo, Ikki Ishida, Moeko Hiraishi, Toshiya Teraishi, Kotaro Hattori, Hiroshi Kunugi Source Type: research