The Clinical Spectrum and Manifestations of Acute Liver Failure

Acute liver failure (ALF) is a rare life-threatening condition characterized by rapid progression and death. Causes vary according to geographic region, with acetaminophen and drug-induced ALF being the most common causes in the United States. Determining the cause aids in predicting the prognosis and the presentation of manifestations and guides providers to perform cause-specific management. At initial presentation, nonspecific symptoms are present but may progress to complications, including cerebral edema, infection, coagulopathy, renal failure, cardiopulmonary failure, and acid-base and/or metabolic disturbances. Although some cases of ALF resolve with conservative measures, liver transplantation is the ultimate treatment in many cases.
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research

Related Links:

On February 11, the Trump administration issuedfunding opportunity announcements for the Teen Pregnancy Prevention Program (TPPP) that indicate a step away from abstinence-only-until-marriage approaches that the administration has been pushing for years.
Source: The Guttmacher Institute - Category: International Medicine & Public Health Authors: Source Type: news
The number of citations a publication receives has been regarded as one measure of its importance and clinical impact. However, studies have yet to investigate which characteristics are predictors of citation rates within the spine subspecialty literature. To explore this topic, all articles published in 2010 in Spine and from 2010 to 2011 in The Spine Journal and the Journal of Neurosurgery: Spine were reviewed. The Web of Science search engine was used to determine the number of times each article was cited in the 5 years following its publication. Sample characteristics were collected and were compared with a χ2 tes...
Source: Journal of Spinal Disorders and Techniques - Category: Surgery Tags: Research Methodology Source Type: research
Condition:   Alcohol-related Liver Disease Intervention:   Drug: Acomprosate Sponsor:   Mayo Clinic Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Nausea;   Vomiting;   Anxiety State Intervention:   Other: Inhalation aromatherapy with orange essential oil Sponsor:   Hacettepe University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Rahim MA, Zaman S, Amin MR, Uddin KN, Ma JC Abstract Histoplasmosis is uncommon in many parts of the world, including Bangladesh, where, in recent years, cases are increasingly reported. We sought to describe the sociodemographic characteristics, clinical presentation, investigations, treatment, and outcome of histoplasmosis in Bangladesh. We conducted a retrospective data review of published literature from 1962 to 2017, containing information on histoplasmosis in and/or from Bangladesh. Unpublished, well-documented histoplasmosis cases were also included. A total of 26 male patients aged 8-75 years, with...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
Conclusions This is the first study to examine the patient's perspective of self-efficacy in the acute phase of HSCT. This contributes to existing literature on the concept of symptom management and expands nursing knowledge of SESM in patients undergoing HSCT. Implications for Practice Nurses can assess SESM before transplantation and implement interventions to enhance SESM when symptoms are at their most distressing after HSCT. The findings from this study can provide the basis for creating behavioral interventions to enhance self-efficacy for symptom management in HSCT patients.
Source: Cancer Nursing - Category: Nursing Tags: ARTICLES: ONLINE ONLY Source Type: research
CDC officials have warned that the novel coronavirus is likely to spread in communities in the United States. Here are 10 questions answered about how to prepare and protect yourself and your family.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
ConclusionsThe differential antagonism of rate ‐decreasing and hypothermic effects implicates differential involvement of nAChR subtypes. The decreased capacity of mecamylamine and DHβE to antagonize nicotine during chronic nicotine treatment may indicate that their effectiveness as smoking cessations might vary as a function of nicotine tole rance and dependence.
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
This study highlighted sex differences in areas that could account for the underuse of the procedure in both sexes, with women affected to a greater extent. Understanding these factors will help address the unmet needs of both sexes after TJA by encouraging future studies and provider education to ensure that all patients are able to access the necessary procedures for pain relief and functional improvement. PMID: 32015251 [PubMed - as supplied by publisher]
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
Conclusion: The Mtb infection status had a significant impact on mycobacterial growth inhibition in PBMC from healthy adults in South Korea, a country with an intermediate burden of tuberculosis, with healthy controls showing the greatest mycobacterial growth inhibition. Introduction Pulmonary tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis (Mtb), which is a significant burden for the world, reaching 9.6 million new TB cases and 1.5 million deaths per year (1). Also, just under a quarter of the global population is latently infected with Mtb, and 5–10% of them will dev...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
More News: Acetaminophen | Cardiology | Gastroenterology | Heart | HIV AIDS | Liver | Liver Disease | Liver Transplant | Lortab | Renal Failure | Transplants | Urology & Nephrology | USA Health