Influence of MP 29-02 on ciliary beat frequency in human epithelial cells in vitro

ConclusionsMP 29-09 significantly reduced CB, with an almost linear relationship between the MP 29-09 concentration and reduction in CBF. For fluticasone propionate, a significant reduction of CBF was observed only at the highest analyzed concentration. The findings have implications for the long-term use of the MP 29-02. Yet, further clinical studies are needed to confirm these results in vivo, especially in patients with seasonal or perennial allergic rhinits.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research