Report: Next Pandemic Will Likely Be Respiratory-Based Virus

(MedPage Today) -- Experts argue that increased surveillance on a clinical and public health level is critical
Source: MedPage Today Public Health - Category: American Health Source Type: news

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Authors: Feldman C, Shaddock E Abstract INTRODUCTION: Lower respiratory tract infections (LRTIs) are the leading infectious disease cause of death in the world and the fifth overall cause of death. From an epidemiological point of view, most consider pneumonia, influenza, bronchitis (including acute exacerbations in chronic obstructive pulmonary disease [AECOPD]), and bronchiolitis to be the most important LRTIs. Areas covered: This review will describe the epidemiology of LRTIs in adults focusing on community-acquired pneumonia, influenza, and AECOPD, utilizing data from the more recent literature. Expert commenta...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
Publication date: Available online 6 December 2018Source: CellAuthor(s): Nicolás Rascovan, Karl-Göran Sjögren, Kristian Kristiansen, Rasmus Nielsen, Eske Willerslev, Christelle Desnues, Simon RasmussenSummaryBetween 5,000 and 6,000 years ago, many Neolithic societies declined throughout western Eurasia due to a combination of factors that are still largely debated. Here, we report the discovery and genome reconstruction of Yersiniapestis, the etiological agent of plague, in Neolithic farmers in Sweden, pre-dating and basal to all modern and ancient known strains of this pathogen. We investigated the histor...
Source: Cell - Category: Cytology Source Type: research
ConclusionOur study highlights the involvement ofp-IRS-1/p-Akt/GLUT-4, leptin/STAT-3 and SREBP-1c signaling trajectories in the beneficial combination of GC and RK, besides, the efficient rebalance of the redox status, insulin resistance and tissue fat deposition confirmed histopathologically.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Authors: Kim H, Chung MS Abstract Antiviral activities of Morus alba (MA) juice and seed were examined using time-of-addition plaque assays against influenza viruses, A/Brisbane/59/2007 (H1N1) (BR59), pandemic A/Korea/01/2009(H1N1) (KR01), A/Brisbane/10/2007(H3N2) (BR10), and B/Florida/4/2006 (FL04). MA juice (MAJ) showed much higher antiviral activity than MA seed (MAS). In the pre- and cotreatment of virus, MAJ showed antiviral effects against BR59, KR01, and FL04 in a dose-dependent manner. In particular, MAJ at 4% concentration exhibited 1.3 log inhibition in the pre- and cotreatment of the virus against FL04, ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Life expectancy at birth in the United States fell again in 2017 for the third year running, the longest sustained decline since 1915-18, when the first world war and the 1918 Spanish influenza pandemic were among the causes of death. A continued inc...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
New research suggests that the germ may have devastated settlements across Europe at the end of the Stone Age in what may have been the first major pandemic of human history
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Pandemic could explain crash in European population 5,500 years ago and influx of people from Eurasian steppeAn ancient strain of the plague found in a woman buried in Sweden may be the fatal signature of a devastating pandemic that swept through stone age farmers and set the stage for a massive migration into Europe from the east.Evidence for the grim scenario came to light when scientists ran genetic tests on a 20-year-old woman from a rural farming community who was among 78 people buried in apassage grave in G ökhem in western Sweden.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Genetics Epidemics Sweden Science Biology World news Source Type: news
This study aimed to assess the status of health service utilization provided by the Iranian Ministry of Health and Medical Education (MOHME) for people living with HIV/AIDS (PLWHA) in Iran from 1987 to 2016.MethodsSamples were 30516 patients with HIV/AIDS from 31 Iranian provinces registered in the Iranian health database from 1987 to October 2016. Health care services provided by the MOHME were assessed in terms of age, gender, and the marital status. Descriptive and inferential statistics were used for data analysis and the significance level was set as P 
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
ConclusionThe proposed recommendations should be clearly communicated to the target audience as a reference for preparation of health systems and providers for combating the H1N1 virus.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
S. Cheung et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
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