Report: Next Pandemic Will Likely Be Respiratory-Based Virus

(MedPage Today) -- Experts argue that increased surveillance on a clinical and public health level is critical
Source: MedPage Today Public Health - Category: American Health Source Type: news

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(MedPage Today) -- But not enough information to establish causation
Source: MedPage Today Pulmonary - Category: Respiratory Medicine Source Type: news
Dr Andrew Green, clinical and prescribing lead for the General Practice Committee in the UK, urged doctors to step up their preparations ahead of the flu outbreak this winter.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 21 September 2018Source: The Lancet HIVAuthor(s): Juan P Jaworski, Pedro CahnSummaryThe viral plasticity and the vast diversity of HIV-1 circulating strains necessitates the identification of new approaches to control this global pandemic. New generation broadly neutralising monoclonal antibodies (bnMAbs) against the HIV-1 viral envelope protein (Env) can prevent virus acquisition, reduce viraemia, enhance immunity, and induce the killing of infected cells in animal models of HIV-1 infection. Most importantly, passively administered bnMAbs are effective at decreasing viraemia and delaying...
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
PMID: 30229732 [PubMed - in process]
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research
PMID: 30229731 [PubMed - in process]
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research
The influenza virus is a significant public health concern causing 250,000–500,000 deaths worldwide each year. Its ability to change quickly results in the potential for rapid generation of pandemic strains for which most individuals would have no antibody protection. This pandemic potential highlights the need for the continuous development of new drugs against influenza virus. As an essential component and well established virulence determinant, NS1 (nonstructural protein 1) of influenza virus is a highly prioritized target for the development of anti-influenza compounds. Here, we used NMR to determine that the NS1...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Protein Structure and Folding Source Type: research
Publication date: December 2018Source: Current Opinion in Virology, Volume 33Author(s): Alana Lynn Jacobson, Siobain Duffy, Peter SseruwagiEmerging plant viruses are one of the greatest problems facing crop production worldwide, and have severe consequences in the developing world where subsistence farming is a major source of food production, and knowledge and resources for management are limited. In Africa, evolution of two viral disease complexes, cassava mosaic begomoviruses (CMBs) (Geminiviridae) and cassava brown streak viruses (CBSVs) (Potyviridae), have resulted in severe pandemics that continue to spread and threa...
Source: Current Opinion in Virology - Category: Virology Source Type: research
Although there have been some public reflections on WWI in corporate media, I've come across very little about the 1918 influenza pandemic. Check this out:The blue line is the age-adjusted death rate in the United States, and the orange line is life expectancy at birth. They've both been going in the right direction throughout the 20th Century, and most of the 21st until the past few years (more on that later), but as you can see in 1918 we spiked right back into the 19th. Our best estimates are that 50 million people died in the epidemic worldwide, and 675,000 in the U.S. The spike in deaths wasn't caused by the war, per ...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Source: ScienceNOW - Category: Science Authors: Tags: books Source Type: news
AbstractThrombotic microangiopathy (TMA) refers to phenotypically similar disorders, including hemolytic uremic syndromes (HUS) and thrombotic thrombocytopenic purpura (TTP). This review explores the role of the influenza virus as trigger of HUS or TTP. We conducted a literature survey in PubMed and Google Scholar using HUS, TTP, TMA, and influenza as keywords, and extracted and analyzed reported epidemiological and clinical data. We identified 25 cases of influenza-associated TMA. Five additional cases were linked to influenza vaccination and analyzed separately. Influenza A was found in 83%, 10 out of 25 during the 2009 ...
Source: Pediatric Nephrology - Category: Urology & Nephrology Source Type: research
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