Impaired Tongue Function as an Indicator of Laryngeal Aspiration in Adults with Acquired Oropharyngeal Dysphagia: A Systematic Review

AbstractTongue function assessment typically forms part of a clinical bedside swallowing evaluation (CBSE). The predictive value of lingual function for calculating aspiration risk in isolation is not known. The aim of this systematic review was to collate current evidence on the utility of assessing lingual deficits for predicting aspiration. Health databases Medline, CINAHL, Cochrane Library, SpeechBITE, AMED and Embase were searched from inception to November 2016. Studies were included if there was a comparison between a clinical lingual assessment (index test) and aspiration on instrumental assessments (reference test) in adults who had been diagnosed with oropharyngeal dysphagia. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used to assess the quality of the studies. Sensitivity, specificity, predictive values, likelihood ratios and odds ratios were extracted or calculated where possible. A best evidence synthesis and receiver operator curve (ROC) analysis for sensitivity and specificity were conducted. Twelve studies were included, of which only one had a low risk of bias. The ROC curve, predictive values and likelihood ratios did not show a relationship between lingual function and aspiration. Best evidence synthesis showed moderate evidence that when motility and strength are jointly assessed, they are not associated with aspiration. Other lingual assessment variables indicated either limited or conflicting evidence of an association. Ther...
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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Abstract OBJECTIVE: Investigate Vitamin D3 (VD3) effect on the Acetylcholinesterase (AChE), oxidative damage and behavioral tests in animals subjected to Intracerebroventicular injection of Streptozotocin (ICV-STZ) simulating a Sporadic Dementia of Alzheimer's Type (SDAT) and treated with VD3 (21 days). METHODS: Animals were divided into eight groups: Vehicle, VD12.5 μg/kg, VD42 μg/kg, VD125 μg/kg, STZ, STZ+VD12.5 μg/kg, STZ+VD42 μg/kg, STZ+VD125 μg/kg. RESULTS: VD3 prevented the increase in AChE in groups of VD42 µg/kg and VD125 µg/kg; in AChE of synaptossom...
Source: Redox Report : communications in free radical research - Category: Biochemistry Authors: Tags: Redox Rep Source Type: research
Part of our mission at Columbus Business First is to help be a guide to the people you should know in the community through our daily news coverage and our various awards and recognition programs. Here is the complete list of our inaugural Power 100.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Journal Name: Journal of Perinatal Medicine Issue: Ahead of print
Source: Journal of Perinatal Medicine - Category: Perinatology & Neonatology Source Type: research
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Andrew Warner, Kieron M Enright, John M Cole, Kang Yuan, John S McGough, Michael James Ingleson The borylative cyclisation of 1,2-dialkynyl benzenes with BCl3 leads to dibenzopentalenes (via intramolecular SEAr) or benzofulvenes (via chloride addition) depending on substituents, with stabilised vinyl cation intermediates (e.g. with a... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB00836E, CommunicationMingchang Wu, Junhang Yang, Fang Luo, Cungui Cheng, Gangguo Zhu Iron-catalyzed; Knoevenagel-hetero-Diels-Alder reaction; oxabicyclo[3.3.1]nonene; chromene The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
Abstract Based on the experimental data of octanol-water partition coefficients (K ow, represents bioaccumulation) for 13 polychlorinated biphenyl (PCB) congeners, comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used to establish 3D-QSAR models, combined with the hologram quantitative structure-activity relationship (HQSAR), the substitution sites (mono-substituted and bis-substituted) and substituent groups (electron-withdrawing hydrophobic groups) that significantly affect the octanol-water partition coefficients values of PCBs were identified, a t...
Source: Bioscience Reports - Category: Biomedical Science Authors: Tags: Biosci Rep Source Type: research
In this study, the effect of plating temperature on mechanically agitated and ultrasonic assisted electroless nickel-boron deposition was investigated: deposition was performed in two different configurations: one with a classical mechanical agitation at 300 rpm and the other employing ultrasound at a frequency of 35 kHz. In addition, different temperatures in the 80-95 °C range were tested. The increase of plating rate previously observed was confirmed and it was possible to lower slightly plating temperature while conserving plating efficiency, which decreases evaporation of the solution. Morphological, mechani...
Source: Ultrasonics Sonochemistry - Category: Chemistry Authors: Tags: Ultrason Sonochem Source Type: research
Abstract A simple and facile ultrasound based sonochemical method to incorporate Perovskite-type barium titanate (BaTiO3) nanoparticles inside the layered and reduced graphene oxide sheets (rGOs) is reported. BaTiO3@rGOs nanocomposite was characterized by FESEM, HRTEM, EDX, mapping, XRD, XPS and EIS. The results show that the decoration and also incorporation of BaTiO3 nanoparticles in the multi-layered and ultrasound reduced graphene oxide matrix. Non-enzymatic and differential pulse voltammetric sensor of ractopamine (food toxic) based on the BaTiO3@rGOs nanocomposite modified screen printed carbon electrode is ...
Source: Ultrasonics Sonochemistry - Category: Chemistry Authors: Tags: Ultrason Sonochem Source Type: research
This study demonstrated that airborne acoustic technology can be employed for microbial inactivation of dried food ingredients with minimal impacts on food quality. PMID: 31101268 [PubMed - in process]
Source: Ultrasonics Sonochemistry - Category: Chemistry Authors: Tags: Ultrason Sonochem Source Type: research
Abstract A novel ferrocene-functionalized silver cluster (FcAgCs) has been designed and synthesized with the assistant of ultrasound treatment and fully characterized by single crystal spectroscopy, IR, UV-Vis, XRD, TGA, NMR, CV and elemental analyses. Ultrasound synthesis method facilitates and accelerates synthesis of this amazing structure and plays a vital role in the synthesis of this special cluster. Single-crystal X-ray analysis reveal that the cluster can be described as a cationic [(dppf)2Ag4(CCtBu)2(CH3OH)2]2+ (dppf = 1,1'-bis(diphenylphosphino)ferrocene) species consisted of four rhombic silver atom...
Source: Ultrasonics Sonochemistry - Category: Chemistry Authors: Tags: Ultrason Sonochem Source Type: research
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