Saliva Production and Enjoyment of Real-Food Flavors in People with and Without Dysphagia and/or Xerostomia

This study examined palatability and saliva flow associated with dissolvable flavored films. Taste strips with real-food flavors dissolved on the tongues of 21 persons with dysphagia and/or xerostomia and 21 healthy age- and sex-matched adults while sublingual gauze pads absorbed saliva over randomized 3-min trials. Participants rated taste enjoyment for each trial on a hedonic general labeled magnitude scale. Flavored strips elicited more saliva than baseline for both groups, and production was higher for controls than patients (M = 2.386 and 1.091 g, respectively;p  =  0.036). Main effects of flavor were observed for saliva production (p  =  0.002) and hedonics (p  
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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ABSTRACT Objective: Chronic kidney disease is characterized by progressive and irreversible loss of kidney function. The impact of this disease on oral health also presents controversial results. The aim of the study was to determine oral health conditions and oral symptoms of patients with Chronic kidney disease undergoing hemodialysis. Methods: A cross-sectional study on a population with chronic renal failure was performed. Anamnesis and oral examination, decayed, miss and filled teeth (DMFT) index, community periodontal index, simplified oral hygiene index (OHI-S) and gingival index were conducted. Data were processed ...
Source: RGO - Revista Gaucha de Odontologia - Category: Dentistry Source Type: research
Publication date: Available online 10 August 2018Source: Autoimmunity ReviewsAuthor(s): Konstantia Psianou, Ioannis Panagoulias, Anastasios D. Papanastasiou, Anne-Lise de Lastic, Maria Rodi, Panagiota I. Spantidea, Søren E. Degn, Panagiotis Georgiou, Athanasia MouzakiAbstractSjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine glands, resulting in their functional impairment. In SS, lymphocytic infiltration of salivary and lacrimal glands, and deposition of several types of autoantibodies, mainly anti-SS-A (anti-Ro) and anti-SS-B (anti-La), lead to chronic inflammation, wi...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
CONCLUSION: The inclusion of NTZ to CCRT is more effective for long-term survival among LA-NPC patients than CCRT only. PMID: 30081714 [PubMed - as supplied by publisher]
Source: Cancer Biology and Therapy - Category: Cancer & Oncology Authors: Tags: Cancer Biol Ther Source Type: research
CONCLUSIONS: Selective SPECT/CT-guided ENI results in significant dose reductions to various organs-at-risk and corresponding NTCP values, and will subsequently reduce the incidence and severity of different troublesome radiation-related toxicities and improve quality-of-life. PMID: 30087057 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
Conditions:   Xerostomia;   Sjogren's Syndrome Interventions:   Other: Mouthwash treatment;   Other: Toothpaste treatment;   Other: Mouthwash placebo;   Other: Toothpaste placebo Sponsor:   Rosa María López-Pintor Muñoz Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, FS questionnaire linked to the “dry mouth” syndrome is strongly recommended for application in primary healthcare. Consequently, targeted preventive measures can be triggered early in life. For example, traditional, complementary and alternative me dicine demonstrates positive therapeutic effects in individuals suffering from xerostomia. For in-depth diagnostics, epi/genetic regulations involved into pathophysiologic mechanisms of hyposalivation in FS-affected individuals should be thoroughly investigated at molecular level. Identified biomark er panels might be of great clinical utility for pred...
Source: EPMA Journal - Category: International Medicine & Public Health Source Type: research
Conditions:   Xerostomia;   Asialia;   Hyposalivation;   Mouth Dryness Interventions:   Dietary Supplement: Aqualief;   Other: Placebo Sponsors:   Helsinn Healthcare SA;   Latis S.r.l. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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