PLOS ONE publishes a howler of a bad acupuncture network meta-analysis

Meta-analyses can sometimes suffer from the “GIGO problem” (garbage in, garbage out). The publication of a “crappy” acupuncture “network meta-analysis” for acupuncture and chronic constipation illustrates the GIGO problem on steroids a.nd reveals a problem with peer review at PLOS ONE, where it was published The post PLOS ONE publishes a howler of a bad acupuncture network meta-analysis appeared first on RESPECTFUL INSOLENCE.
Source: Respectful Insolence - Category: Surgery Authors: Tags: Bad science Clinical trials Integrative medicine Quackery acupuncture electroacupunture featured meta-analysis PLoS ONE Source Type: blogs

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We describe the protocol for a randomized, patient-assessor-blinded, sham controlled trial. Seventy-two eligible patients will be randomly assigned to the intervention group (acupuncture) or the control group (sham acupuncture). All treatment will be given 26 sessions of acupuncture or sham acupuncture over 8 weeks (5 times per week in the first 2 weeks, 3 times per week during weeks 3-6, and 2 times per week during weeks7 and 8). Each treatment will last for 20 minutes. The primary outcome is the change in mean complete spontaneous bowel movements (CSBMs) per week. The secondary outcomes are patient assessment of constipa...
Source: World Journal of Acupuncture Moxibustion - Category: Complementary Medicine Source Type: research
Karin Meissner1,2*, Nicola Talsky1, Elisabeth Olliges1,2, Carmen Jacob1,3,4, Oliver J. Stötzer5, Christoph Salat5, Michael Braun6 and Raluca Flondor1 1Institute of Medical Psychology, Faculty of Medicine, LMU Munich, Munich, Germany 2Division of Health Promotion, Coburg University of Applied Sciences, Coburg, Germany 3Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom 4Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom 5Haematology and Oncology, Outpatient Cancer Ca...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
This study focused on sustained complete spontaneous bowel movements (CSBMs) responders over the 8-week treatment. Results: The primary outcome which was percentage of the sustained CSBMs responders for the subset of women with severe constipation was significantly higher in the EA group (24.3%) than in the SA group (8.1%) with difference of 13.1% (95%CI, 6.5% to 19.7%; P
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Conclusion: The conclusion of this systematic review will provide evidence to judge whether acupuncture is an effective therapeutic intervention for patients with uterine fibroids. Trial registration number: PROSPERO CRD42019120484.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
AbstractObjectiveTo observe the effects of electroacupuncture (EA) of different frequencies on the expression levels of substance P (SP) and vasoactive intestinal peptide (VIP) in the colon of rats with slow transit constipation (STC).MethodsOne hundred healthy male Sprague-Dawley (SD) rats were randomly divided into a normal group, a model group, a low-frequency EA group, a high-frequency EA group and a variable-frequency EA group, with 20 rats in each group. The rats in the normal group were fed with normal diet. The rats in the other groups were fed with phenethylpiperidine in the diet at a dose of 8 mg/(kg ·bw) ...
Source: Journal of Acupuncture and Tuina Science - Category: Complementary Medicine Source Type: research
Background: Pain is one of the major comorbidities of sickle cell disease (SCD), which largely remains reliant on opioid use for analgesia. Side effects of opioids including, but not limited to fear of addiction, constipation, pruritus and opioid-induced hyperalgesia warrant the need for analgesic therapies devoid of side effects. Non-pharmacological strategies including acupuncture have been effective in pain treatment. A retrospective analysis (n=24 patients) showed that acupuncture reduced pain in a majority (75%) of SCD patients (Lu K et al., Clin J Pain. 2014). In a mouse model of SCD, electroacupuncture (EA) on consc...
Source: Blood - Category: Hematology Authors: Tags: 113. Hemoglobinopathies, Excluding Thalassemia-Basic and Translational Science: Poster I Source Type: research
(Natural News) Functional constipation is a pain in the butt. Not only does it disrupt your life, but it can bring about much more serious problems. South Korean researchers therefore looked into the possibility of using acupuncture to improve constipation. Acupuncture is one of the many techniques that traditional Korean medicine borrowed from its Chinese...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
This study will provide evidence of the preliminary effects and inform future sample size calculations for studies of acupuncture for constipation following an ischemic stroke. These findings will inform subsequent large-scale randomized controlled trials.Trial registrationISRCTN,22214747. Registered on 17 August 2015.
Source: Trials - Category: Research Source Type: clinical trials
Conclusion: The conclusion of our systematic review will provide evidence to judge whether EA is an effective intervention for patient with IBS. PROSPERO registration number: PROSPERO CRD42018081610.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Conclusion: There is a lack of conclusive evidence regarding the benefits of acupuncture for the treatment of breast cancer survivors in Korea. More rigorous RCTs are necessary in the future to establish stronger clinical evidence regarding the use of acupuncture to better reflect the clinical context of Korea.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
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