Pancreatic cancer foiled by a switch of tumour subtype

Pancreatic cancer foiled by a switch of tumour subtypePancreatic cancer foiled by a switch of tumour subtype, Published online: 14 May 2018; doi:10.1038/d41586-018-05129-6Mutations in the gene KDM6A drive an aggressive subtype of pancreatic cancer by causing repositioning of an enzyme complex that modifies histone proteins associated with DNA, leading to altered gene expression.

https://www.nature.com/articles/d41586-018-05129-6

Source: Nature AOP - May 14, 2018 Category: Research Authors: Fieke Froeling David Tuveson Source Type: research