His Tooth is Funny Looking. What is It?
Discussion Teeth are specialized anatomic parts of the human body that are developed between the ectoderm and ecomesenchyme in a complex process called odontogenesis. More than 300 genes have been identified that influence odontogenesis. Dental abnormalities can have significance for cosmesis, malocclusion, dental caries and periodontal diseases. It is not uncommon for more than 1 area to be affected. For example, Hutchinson teeth which are caused by congenital syphilis are smaller with wider spacing between the teeth within the arch, and also have a characteristic notching. Learning Point Some common dental problems that may be seen or heard about by pediatricians include: Tooth eruption Ankylosis Natal teeth Usually prematurely erupted primary teeth that are present at birth Neonatal teeth erupt in first month Usually lower incisors (85%) and maxillary incisors (11%) Developmental issues Number Anodontia No teeth Hypodontia 1 or more fewer teeth Common, usually in permanent dentitia Etiology – genetic and includes: Albright hereditary osteodystrophy Crouzon’s syndrome Down syndrome Ectodermal dysplasia Ellis-van Creveld Hallermann-Streiff Incontinentia pigmenti Progeria Hyperdontia Increased number of teeth More common in permanent teeth especially maxillary incisors Etiology includes: Apert syndrome Cleidocranial dysplasia Craniometaphyseal dysplasia Oral-Facial-Digital Size Microdontia Smaller teeth than usual, generally uncommon Maxillary...
Conditions: Polycystic Ovary Syndrome; Dental Caries; Oxidative Stress Intervention: Diagnostic Test: polycystic ovary syndrome Sponsor: Recep Tayyip Erdogan University Training and Research Hospital Recruiting
Authors: Filipe R, Aguiar P Abstract INTRODUCTION: A dental voucher was created to facilitate the access to oral health care, however the use of these vouchers, by students aged 7, 10 and 13 with dental caries from state schools within the geodemographic area covered by the Community Health Center Group of Western Lisbon and Oeiras, had a low uptake (23%, school year 2014/2015) The aim of this study was to examine the factors associated with this non-use. MATERIAL AND METHODS: A case-control study was carried out involving 270 students (135 cases and 135 controls) from 35 state schools who agreed to participate...
In this study, we evaluated the activity of ClyR, a well-known chimeric lysin with extended streptococcal host range, against common Gram-positive oral microbes and its anticaries efficacy in rat models. ClyR demonstrated high lytic activity against S. mutans MT8148 and S. sobrinus ATCC6715, with minor activity against Streptococcus sanguinis, Streptococcus oralis, and Streptococcus salivarius, which are considered as harmless commensal oral bacteria. Confocal laser scanning microscopy showed that the number of viable cells in 72-h aged S. mutans and S. sobrinus biofilms are significantly (p < 0.05) decreased after ...
Conclusion: Attempts at improving the knowledge and attitude in parents have a substantial impact on improving the oral health of next generation.
Conclusion: There was a strong correlation between dermatoglyphic patterns (especially ulnar loops, whorls and total ridge count), dental caries and S. mutans level.
----Searching for the fundamental mental processes that cut across diagnostic categories, driving confusion and distress //BPS Research DigestA new paper in Journal of Clinical Psychology is the just the latest to take a trans-diagnostic approach to mental healthBy Alex FraderaThe number of psychiatric diagnoses keep on growing, with perhaps ten times as many categories now as there were 50 years ago. This may in part reflect our growing knowledge, which is welcome. But the sheer density of diagnoses makes it difficult for researchers or clinicians to see the wood for the trees, and it encourages them to settle into s...
Journal of Intellectual Disability Research, EarlyView.
The placentas of Down syndrome (DS) pregnancies exhibit morphologic and functional abnormalities. Although the increase in dosage of certain genes on chromosome 21 has been associated with the DS phenotype, the effects on placenta have seldom been studied. Here we examine the expression of four dosage sensitive genes APP, ETS2, SOD1, and HMGN1 in normal and DS placentas. We demonstrated significant overexpression of amyloid precursor protein (APP) in DS placentas at RNA and protein levels by qPCR, western blot, and immunohistochemistry.
Lasers in Surgery and Medicine, EarlyView.
ConclusionsBecause dental anomalies, especially radiculomegaly, are a primary feature of OFCD syndrome, dentists should be aware of the clinical and radiographic features. Radiculomegaly poses a distinct challenge to dentists, and reports of dental therapy provided to these patients are sparse. Early diagnosis of the syndrome may prevent dental challenges and improve prognosis.
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