Chromatography of oxysterols.

CHROMATOGRAPHY OF OXYSTEROLS.
Biochimie. 2018 May 08;:
Authors: Dias IHK, Wilson SR, Roberg-Larsen H
Abstract
Oxysterols play important roles in development and diseases, but can be highly challenging to analyze. To ensure satisfactory measurements, oxysterols must typically be separated with chromatography prior to detection. Here, we will devote attention to the chromatography of oxysterols, focusing on gas chromatography and liquid chromatography. We will present the role of stationary phases, mobile phases, and dimensions and geometries of particles/columns. We discuss how these parameters may affect the chromatography, regarding factors such as speed and resolution. Finally, we present some less explored avenues for separation of oxysterols.
PMID: 29751082 [PubMed - as supplied by publisher]

Source: Biochimie - May 8, 2018 Category: Biochemistry Authors: Dias IHK, Wilson SR, Roberg-Larsen H Tags: Biochimie Source Type: research