Hyponatremia Predicts Poor Outcomes in Patients with Chronic Kidney Disease Undergoing Heart Surgery.

Hyponatremia Predicts Poor Outcomes in Patients with Chronic Kidney Disease Undergoing Heart Surgery. Ann Thorac Surg. 2018 May 08;: Authors: Shavit L, Merin O, Grenader T, Jacobson E, Waldenberg C, Bitran D, Fink D, Silberman S Abstract BACKGROUND: Preoperative hyponatremia adversely impacts outcomes of cardiothoracic surgery. However, in patients with chronic kidney disease, the association of sodium levels on postoperative events has never been evaluated. We investigated the impact of preoperative hyponatremia on outcomes after cardiac surgery in patients with non-dialysis-dependent chronic kidney disease. Primary endpoints were operative mortality and acute kidney injury requiring dialysis. Secondary endpoints were major infection and long-term survival. METHODS: The study is observational and includes all patients with stage III-IV chronic kidney disease (non-dialysis) undergoing cardiac surgery between February 2000-January 2016. Patients were stratified into 2 groups by preoperative sodium levels: Na
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research

Related Links:

This article reviews the clinical case for a special emphasis on this transition period, reviews published literature regarding prior transitional care programs, and proposes a novel iteration of the first 30 days of dialysis care: the transitional care unit (TCU). The goal of a TCU is to improve awareness of all aspects of renal replacement therapy, including modalities, access, transplantation options, and nutritional and psychosocial aspects of the disease. This enables patients to make truly informed decisions regarding their care. The TCU model is open to all patients, including incident patients with end-stage renal ...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
ConclusionsAmong incident patients with ESRD with diabetes, a dose-dependent relationship between frequency of pre-ESRD hypoglycemia-related hospitalizations and post-ESRD mortality was observed. Further study of diabetic management strategies that prevent hypoglycemia as patients with chronic kidney disease transition to ESRD are warranted.
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: Available online 19 July 2018Source: Canadian Journal of CardiologyAuthor(s): Lorenzo Azzalini, Soledad Ojeda, Ozan M. Demir, Joseph Dens, Masaki Tanabe, Alessio La Manna, Susanna Benincasa, Barbara Bellini, Enrico Poletti, Davide Maccagni, Francisco Hidalgo, Jorge Chavarría, Joren Maeremans, Giacomo Gravina, Eligio Miccichè, Guido D’Agosta, Giuseppe Venuti, Corrado Tamburino, Manuel Pan, Mauro CarlinoAbstractBackgroundChronic total occlusion (CTO) percutaneous coronary intervention (PCI) is associated with high contrast volumes, which can be particularly deleterious in chronic kidney ...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
AbstractPurpose of ReviewThe choice of optimum transplant in a patient with type 1 diabetes mellitus (T1DM) and chronic kidney disease stage V (CKD V) is not clear. The purpose of this review was to investigate this in more detail —in particular the choice between a simultaneous pancreas-kidney transplantation (SPKT) and living donor kidney transplantation (LDKT), including recent evidence, to aid clinicians and their patients in making an informed choice in their care.Recent FindingsAnalyses of large databases have recently shown SPKT to have better survival rates than a LDKT in the long-term, despite an early incre...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
Authors: Ogunleye A, Akinbodewa AA, Adejumo OA, Oluwafemi TT, Akinfaderin DA Abstract Oxidative stress has been implicated in the pathogenesis, progression of chronic kidney disease (CKD) and development of cardiovascular complications. Hemodialysis (HD) has also been described to contribute significantly to oxidative stress in CKD patients, though reports are conflicting. Objective: We evaluated the effects of one session of HD on the antioxidant capacity and lipid peroxidation in CKD patients. Method: Thirty-six CKD patients requiring HD were recruited into this study. Participants were naïve to HD a...
Source: Ghana Medical Journal - Category: African Health Tags: Ghana Med J Source Type: research
Therapeutic Apheresis and Dialysis, EarlyView.
Source: Therapeutic Apheresis and Dialysis - Category: Hematology Authors: Source Type: research
Authors: Patel J, Bridgeman MB Abstract Etelcalcetide (Parsabiv) for hyperparathyroidism in adults with chronic kidney disease on hemodialysis. PMID: 30013296 [PubMed]
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
AbstractManagement of hyperphosphatemia in patients with dialysis-dependent chronic kidney disease remains a major challenge, requiring a multifaceted approach that includes dietary phosphate restriction, dialysis, and phosphate binders. However, these treatments fail to meet serum phosphate targets in many patients, potentially further exacerbating the significant morbidity and mortality burden associated with the disease. Recent advances in our understanding of the mechanisms underlying phosphate homeostasis have shed new light on the issue and suggest that gastrointestinal transport proteins may be promising targets for...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
This study introduces a novel concept underlying the basis for maturational and functional failure in human dialysis AVFs and identifies a new target for senolytic therapy. PMID: 30019935 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Renal Physiology - Category: Physiology Authors: Tags: Am J Physiol Renal Physiol Source Type: research
Conclusions: This is the first Italian prospective study performed with a large cohort of CKD patients over a 3-year period. Considering the multifactorial burden of diseases associated with CKD patients, the need for greater attention to CKD and related disorders is paramount.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
More News: Cardiology | Cardiovascular & Thoracic Surgery | Chronic Kidney Disease | Dialysis | Heart | Sodium | Study | Urology & Nephrology