SPIN1, negatively regulated by miR-148/152, enhances Adriamycin resistance via upregulating drug metabolizing enzymes and transporter in breast cancer.

CONCLUSIONS: Our results establish that SPIN1, negatively regulated by the miR-148/152 family, enhances Adriamycin resistance in breast cancer via upregulating the expression of drug metabolizing enzymes and drug transporter. PMID: 29743122 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29743122?dopt=Abstract

Source: Clinical Breast Cancer - May 9, 2018 Category: Cancer & Oncology Authors: Chen X, Wang YW, Gao P Tags: J Exp Clin Cancer Res Source Type: research

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