Prevalence of multiple infections and the risk of gastric adenocarcinoma development at earlier age

Helicobacter pylori and Epstein-Barr virus are well established infections for gastric cancer development. However, the role of cytomegalovirus alone or in combination with other infections is unclear. In this case-control study the prevalence of different infections was evaluated and their frequency was compared with clinicopathologic features among gastric cancer patients and normal volunteers from 2012 to 2017. Approximately two-third (61.9%) of the gastric cancer patients had at least one viral infection, while viral infection prevalence in normal volunteers was only 4.7% (P = 0.021).

Source: Diagnostic Microbiology and Infectious Disease - May 11, 2018 Category: Microbiology Authors: Sadegh Fattahi, Novin Nikbakhsh, Hassan Taheri, Elham Ghadami, Mohadeseh Kosari-Monfared, Galia Amirbozorgi, Mohsen Asouri, Maryam Pilehchian-Langroudi, Mohammad Ranaee, Ali Akbar Samadani, Mahdi Paryan, Haleh Akhavan-Niaki Source Type: research