The effectiveness and safety of nonsurgical integrative interventions for symptomatic lumbar spinal spondylolisthesis: A randomized controlled multinational, multicenter trial protocol

Conclusion and discussion: The results of this study will provide clinical evidence on nonsurgical integrative interventions for patients with symptomatic lumbar spondylolisthesis. Clinical trial registry: clinicaltrials.gov (NCT03107468)
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

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Authors: Gentile E, Ricci K, Delussi M, Brighina F, de Tommaso M Abstract Previous studies indicated changes of motor cortex excitability in fibromyalgia (FM) patients and the positive results of transcranial stimulation techniques. The present study aimed to explore the metabolism of motor cortex in FM patients, in resting state and during slow and fast finger tapping, using functional Near-Infrared Spectroscopy (fNIRS), an optical method which detects in real time the metabolism changes in the cortical tissue. We studied 24 FM patients and 24 healthy subjects. We found a significant slowness of motor speed in FM ...
Source: Pain Research and Treatment - Category: Anesthesiology Tags: Pain Res Treat Source Type: research
The indications for cryoablation in pediatric patients has been slowly growing over the last few years. Vascular anomalies and solid tumors are being treated with this modality. However, cryoablation can be associated with local complications. This is of high relevance in children due to smaller body surface area, more compact anatomy and less subcutaneous fat. Additionally, these patients have lower tolerance to pain and inflammation. It is critical to understand these factors when using cryoablation to treat pediatric patients.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 5: You ’ve Got To Be Kid-ing Me (Pediatric IR) Source Type: research
Knee OA is a common cause of pain and disability, with many patients relying on chronic pain medications and/or joint injections. These options unfortunately result in short-term relief, or have associated increased morbidity, and knee replacement surgery may ultimately be performed. Researchers have postulated that synovial neovascularity develops as a result of inflammation and subsequently leads to knee pain. While previous overseas reports of success with GAE have been published, we present our final results from a prospective US multicenter clinical trial.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 3: Not Your Run-of-the-Mill Embolization Source Type: research
The most common clinical presentation of peripheral artery disease (PAD) comprises intermittent claudication though about one third of patients will progress to below-the-knee critical limb ischemia. Currently, percutaneous transluminal angioplasty (PTA) is the standard endovascular therapy employed in this patient population. The Lutonix BTK  IDE multicenter randomized study was conducted to assess the safety and efficacy of the Lutonix DCB for the treatment of stenosis or occlusion of native below-the-knee arteries.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 2: Finish the Race Source Type: research
There are no reported descriptions of motor nerve cryoablation in humans. As a result, physicians faced with inadvertent motor nerve cryoablation during palliative or therapeutic procedures for established indications are forced to rely on preclinical studies to manage patient expectations. (1, 2) In addition, potential applications of motor nerve cryoablation, such as for management of spasticity and pain, have been avoided because of the unknown prognosis following cryoneurolysis of mixed or motor nerves.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 41: Other Nonvascular Interventions Source Type: research
Ultrasound image-guided procedures (USGP) are common and often cause mild to moderate pain both during the procedure and during lidocaine injection. This 110 participant randomized clinical trial evaluated the effectiveness of vapocoolant topical anesthetic application prior to lidocaine injection at reducing pain during the USGP.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 41: Other Nonvascular Interventions Source Type: research
To examine the efficacy of image-guided percutaneous interventions in pain and local tumor control in the treatment of osseous metastases from breast cancer.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 31: You ’re So Hip (MSK) Source Type: research
To evaluate the outcomes after computed tomography (CT)-guided sacroiliac (SI) joint injections in patients suspected to have lower back pain from SI joint instability.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 31: You ’re So Hip (MSK) Source Type: research
Percutaneous vertebroplasty (PV) is an alternative option to treat pain after an osteoporotic vertebral compression fracture (OVCF). Controversy exists as to whether PV increases the risk for new OVCFs or prevents further vertebral height loss in treated levels. We assessed both during one year follow-up in patients with acute OVCF randomised to PV or a sham procedure.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 31: You ’re So Hip (MSK) Source Type: research
To analyze the safety and efficacy of image-guided genicular nerve radiofrequency ablation (RFA) for the treatment of pain in non-surgical candidates with moderate to severe knee osteoarthritis (OA).
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 31: You ’re So Hip (MSK) Source Type: research
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