Mitochondrial pathway mediated by reactive oxygen species involvement in α-hederin-induced apoptosis in hepatocellular carcinoma cells.

CONCLUSION: The α-hederin saponin induces apoptosis of HCC cells via the mitochondrial pathway mediated by increased intracellular ROS and may be an effective treatment for human HCC.
PMID: 29740205 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - May 7, 2018 Category: Gastroenterology Authors: Li J, Wu DD, Zhang JX, Wang J, Ma JJ, Hu X, Dong WG Tags: World J Gastroenterol Source Type: research