Novel Thirdhand Smoke Exposure Route Identified

THS exposure route ID'd from partitioning of surface volatile organic compounds into aerosol phase
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Internal Medicine, Allergy, Pathology, Pediatrics, Pulmonology, Journal, Source Type: news

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ConclusionIn this series, 4% was the cutoff point for the number of eosinophils in the nasal lavage, for atopy differentiation. Upper airway remodeling accessed by basement membrane thickness showed similar inflammatory cell infiltrate in the nasal lavage, regardless of the presence of atopy.ResumoIntroduçãoA extensão da lesão epitelial na rinite alérgica e não alérgica e sua associação com alterações inflamatórias no lavado nasal, ainda não estão esclarecidas.ObjetivoVerificar a relação entre o processo inflamat...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Epicutaneous immunotherapy for peanut allergy resulted in significantly more responses than placebo, but failed to meet a primary trial endpoint; the clinical meaning of the findings is unclear.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Allergy & Clinical Immunology News Source Type: news
Publication date: Available online 21 February 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Daniel J. Jackson, Scott H. Sicherer
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Conclusions: Low-dose and short-term oPSL did not appear to markedly affect the tissue eosinophil count in ECRS patients; however, the potential for misdiagnoses due to the effects of oPSL cannot be rejected. The diagnosis of ECRS prior to the administration of corticosteroids or tissue evaluations using multiple tissue parts is desirable.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
(MedPage Today) -- Patients with late-onset asthma, low lung function most responsive
Source: MedPage Today Allergy - Category: Allergy & Immunology Source Type: news
AbstractPurpose of ReviewPediatric chronic rhinosinusitis (CRS) is a prevalent problem that can elude diagnosis. In addition, given the burgeoning interest in pediatric sinonasal disease, treatment modalities are constantly evolving.Recent FindingsThe diagnosis of pediatric CRS is primarily based on clinical history and signs supported by objective findings (i.e., nasal endoscopy and/or computed tomography (CT) imaging). Cultures are indicated in patients who have not responded to medical therapy or have significant comorbidities. Nasal saline irrigation, nasal saline spray, and oral antibiotics are currently recommended f...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewOur scope is the presentation of research and clinical progresses in relation to precision medicine that are expected to alter our clinical practice in relation to chronic rhinosinusitis (CRS). Current knowledge on phenotypes and endotypes, biomarkers, and clinical markers for diagnosis, medical and surgical therapy, and prognosis is presented as well as the role of precision medicine in United Airway Disease and SCUAD (severe-uncontrolled chronic upper airway inflammation).Recent FindingsCurrent technological progresses, mostly in relation to molecular biology and information technology, have perm...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewPediatric drug hypersensitivity is a rapidly evolving field. The purpose of this paper is to review the current state of pediatric drug hypersensitivity and highlight new developments in diagnosis and management.Recent FindingsThis paper will discuss the safety and use of risk stratification to proceed directly to oral challenge without prior skin testing for β-lactam reactions. We review unique aspects of pediatric drug challenges and desensitizations.SummaryIt is important to accurately diagnose pediatric drug hypersensitivity reactions through a detailed history, physical examination, and a...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewMost children and adolescents with allergic rhinitis (AR) present extra-nasal multimorbid conditions, including conjunctivitis, asthma, atopic dermatitis, rhinosinusitis, or seromucous otitis. Additionally, they may present nasal obstructive disorders, such as septal deformity, turbinate enlargement, and adenoidal hyperplasia, which worsen nasal symptoms, especially nasal obstruction. This is a narrative review on the current state of the concomitant presence of AR and one or more multimorbidities.Recent FindingsThe presence of AR and one or more accompanying multimorbidities is associated to a hig...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewFood allergy is a growing health problem worldwide that impacts millions of individuals. Current treatment options are limited and strict dietary avoidance remains the standard of care. Immunotherapy using whole, native allergens is under active clinical investigation but harbors the risk of severe side effects including anaphylaxis. Newer food-specific therapies with hypoallergenic proteins may potentially offer safer treatment alternatives, and this review seeks to investigate the evidence supporting the use of these modalities.Recent FindingsThe utilization of different methods to alter allergen...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
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