Notes from the Field: Diarrhea and Acute Respiratory Infection, Oral Cholera Vaccination Coverage, and Care-Seeking Behaviors of Rohingya Refugees — Cox’s Bazar, Bangladesh, October–November 2017

Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Source Type: news

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Abstract Pasteurella multocida (P. multocida), a causative agent of fowl cholera, is an important pathogen in the poultry industry. In the present study, we found that the inactivated vaccine of P. multocida grown in an iron-restricted medium provided better protection than that grown in normal medium. Thus, we adopted a comparative proteomics approach, by using two-dimensional gel electrophoresis (2-DE), coupled with matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/TOF MS), to profile the supernatant proteins associated with P. multocida under both conditions. Eleven upregul...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research
Abstract Cholera remains a major public health problem in many developing countries including Bangladesh. The oral cholera vaccine (OCV) is now considered a key component of the public health response to cholera. Although maintaining cold chain and organizing human resource are the major challenges of vaccine delivery to the community. Here we applied an innovative approach to second dose OCV delivery to minimize financial and logistic burdens. The purpose of this study was to assess the feasibility and compliance of second dose self-administration when the second dose was provided in a plastic bag to first dose v...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Abstract The repeated dose toxicity of a prototype cold chain-free, live, attenuated oral cholera vaccine containing 5 × 106 CFU/mL of the VCUSM14P strain was evaluated in Sprague Dawley (SD) rats (single dose administered daily for 30 days) to ascertain its safety for clinical use. Repeated dose toxicity studies for cholera vaccines in the literature have administered 2 or 3 fixed doses at 7, 14, 21 or 69 day intervals. The present study reports an evaluation of 30 repeated doses of cholera vaccine administered at three different concentrations (Group II (1.25 × 106 CFU), Group III (2....
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Abstract We assessed the impact of handwashing promotion on reported respiratory illness as a secondary outcome from among> 60,000 low-income households enrolled in a cluster-randomized trial conducted in Bangladesh. Ninety geographic clusters were randomly allocated into three groups: cholera-vaccine-only; vaccine-plus-behavior-change (handwashing promotion and drinking water chlorination); and control. Data on respiratory illness (fever plus either cough or nasal congestion or breathing difficulty within previous 2 days) and intervention uptake (presence of soap and water at handwashing station) were collecte...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
This article discusses the recent cholera epidemic in Haiti, its origin and spread throughout Haiti, the specific nature and microbiologic characteristics of the pathogen, and ongoing disease management and control efforts. Importantly, this article suggests a future research agenda identifying best strategies for eliminating cholera in Haiti.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Review Articles Source Type: research
AbstractCholera remains a major public health problem in many countries. Poor sanitation and inappropriate clean water supply, insufficient health literacy and community mobilization, absence of national plans and cross-border collaborations are major factors impeding optimal control of cholera in endemic countries.In March 2017, a group of experts from 10 Asian cholera-prone countries that belong to the Initiative against Diarrheal and Enteric Diseases in Africa and Asia (IDEA), together with representatives from the World Health Organization, the US National Institutes of Health, International Vaccine Institute, Agence d...
Source: BMC Proceedings - Category: Biomedical Science Source Type: research
[WHO] "In addition to insecurity and despair, we are faced with shortages of food, we are homeless and worst still, cholera killed my husband last year in Muna IDPs camp" said Munakur Mohammed. Thank God you came to our rescue early this year. My children and I have received the vaccine and we are protected now."
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion: Vaccination coverage on the shores of Lake Chilwa was moderately high and the innovative distribution strategies tailored to people living on the lake provided adequate coverage, even among hard-to-reach communities. Community engagement and simplified delivery procedures were critical for success. Off-label, out-of-cold-chain administration of oral cholera vaccine should be considered as an effective strategy for achieving high coverage in hard-to-reach communities. Nevertheless, coverage and effectiveness must be monitored over the short and long term. PMID: 30505029 [PubMed - in process]
Source: Bulletin of the World Health Organization - Category: International Medicine & Public Health Authors: Tags: Bull World Health Organ Source Type: research
[New Zimbabwe] Local authorities must continue to improve sanitation and the availability of clean water to prevent cholera as vaccination is not 100 percent effective, the World Health Organisation (WHO) has said.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
[New Zimbabwe] Local authorities must continue to improve sanitation and the availability of clean water to prevent cholera as vaccination is not 100 percent effective, the World Health Organisation (WHO) has said.
Source: AllAfrica News: HIV-Aids and STDs - Category: Infectious Diseases Source Type: news
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