Physical dosimetry of volumetric modulated arc therapy (VMAT) using EPID and 2D array for quality assurance

Conclusions Specific QA of VMAT patient (using EPID or 2D array) display great possibility to spare time and to verify individual IMRT fields. 3%/3 mm is the most appropriate of gamma criteria (DD/DTA) for VMAT plans quality assurance. Control charts are a beneficial method for verification assessment for patient specific quality control.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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Conditions:   Acute Leukemia;   Myelodysplastic Syndrome Interventions:   Procedure: Hematopoietic Cell Transplantation;   Radiation: Intensity-Modulated Radiation Therapy;   Radiation: Tomotherapy;   Radiation: Total-Body Irradiation;   Radiation: Volume Modulated Arc Therapy Sponsors:   City of Hope Medical Center;   National Cancer Institute (NCI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsFunctional outcomes after treatment for localized prostate cancer can be predicted at the time of diagnosis based on age, race, PSA, biopsy grade, baseline function, and a general question regarding overall health. Providers and patients can use this prediction tool to inform shared decision making.Patient summaryIn this report, we studied patient-reported sexual, urinary, hormonal, and bowel function through 5 yr after treatment with radical prostatectomy, radiation therapy, or active surveillance for localized prostate cancer. We developed a web-based predictive tool that can be used to predict one’s o...
Source: European Urology - Category: Urology & Nephrology Source Type: research
ConclusionsComplete resection is vital for local control in pancreatic metastasis of UPS. Sites of recurrence are rare; hence, patients must be carefully followed up.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionsThe RT techniques for the treatment of PCa are statistically equivalent with respect to the bRFS rate. This paper confirms that the bRFS rates of Mexican PCa patients who were treated with conventional vs. hypofractionated schemes do not differ significantly.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Conclusion: We recommend the following dose volume objectives for the %RW in order to minimize the risk of LRB after 20-fraction MHRT: V32 ≤ 50%; V50 ≤ 25.8% and V60 ≤ 10%. PMID: 32072030 [PubMed]
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Tags: Clin Transl Radiat Oncol Source Type: research
ConclusionsP-IMRT produces relatively few higher-grade toxicities, and has reasonable disease-related outcomes, especially when delivering using conventionally-fractionated regimens to doses of 45-54 Gy and exercising careful attention to dose constraints during treatment planning. IMRT can thus be considered in well-selected patients in whom adequate survival following pleurectomy is expected. These data also support the initiation of the phase III NRG-LU006 trial of eP/D and chemotherapy with or without IMRT.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Esophageal Squamous Cell Carcinoma Interventions:   Procedure: Intensity modulated radiotherapy (IMRT);   Drug: Chemotherapy Sponsor:   Chinese Academy of Medical Sciences Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractObjectiveIntensity-modulated radiation therapy (IMRT) using a volumetric-modulated arc therapy technique may offer dosimetric and clinical benefits compared to the historical standard of care 3D conformal radiotherapy (3D-CRT) in definitive treatment of bladder cancer. We hypothesized that IMRT with CBCT would reduce dose to the rectum, bowel, and bladder compared to 3D-CRT.MethodsWe reviewed nineteen patients treated with maximal transurethral resection of bladder tumor followed by concurrent chemotherapy with IMRT. All patients received 45  Gy to the entire empty bladder followed by 19.8 Gy tumor boost ...
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research
Radiotherapy causes burdensome side effects that seriously affected the quality of life (QOL). Apolipoprotein B/apolipoprotein A1 (ApoB/ApoA1) ratio was positively correlated with radiotherapy induce brain necrosis (RN) volume and negatively correlated with QOL. ApoB/ApoA1 ratio was an independent risk factor of RN volume, suggesting a bright intervention target in RN treatment. AbstractIntroductionThe apolipoprotein B/apolipoprotein A1 (ApoB/ApoA1) ratio is recognized as a clinical indicator of cardiovascular disease and ischemic cerebral disease. Cerebrovascular dysfunction is also involved in head and neck radiotherapy....
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Publication date: Available online 13 February 2020Source: Practical Radiation OncologyAuthor(s): Eugene J. Koay, Alexander N. Hanania, William A. Hall, Cullen M. Taniguchi, Neal Rebueno, Sten Myrehaug, Katharine L. Aitken, Laura A. Dawson, Christopher H. Crane, Joseph M. Herman, Beth EricksonAbstractPurposeTo provide a detailed description of practical approaches to dose-escalation in pancreatic cancer.Materials/MethodsThe current paper represents an international collaborative effort of radiation oncologists from the MR-linac consortium with expertise in pancreatic dose-escalation. A fifteen fraction hypofractionated int...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
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