Assessment of HMGB-1 concentration in tick-borne encephalitis and neuroborreliosis

A constant increase in the incidence of tick-borne diseases has been observed in Europe since the last decade of the twentieth century. In Poland, the most common zoonoses transmitted by Ixodes ricinus ticks are tick-borne encephalitis (TBE) and Lyme disease. These diseases have become a serious clinical problem, especially in Podlaskie Region, which is considered an endemic area for these diseases (Czupryna et al., 2011).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research

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This report describes the first case of visceral leishmaniasis (VL) resistant to pentavalent antimonials and also the first use of combinational therapy in Iran. The patient was a two-year old boy, from a non-endemic area for leishmaniasis in northern Iran, presenting with pentavalent antimonial resistant VL. Additional treatment with conventional and liposomal amphotericin B was not effective. A complete cure was achieved following a three week treatment with liposomal amphotericin B (5 mg/kg/day for 5 days, then on the 14th and 21st days), allopurinol (25 mg/day for 5 days, then on the 14th and 21st days) and int...
Source: Parasitology International - Category: Parasitology Source Type: research
Publication date: August 2019Source: Biochemical Systematics and Ecology, Volume 85Author(s): Tanja Dodoš, Nemanja Rajčević, Pedja Janaćković, Jelica Novaković, Petar D. MarinAbstractSatureja kitaibelii Wierzb. ex Heuff. is endemic species of central Balkan that lives along the Balkan mountains range. The aim of this research was to study the variability of n-alkane profiles of four S. kitaibelii populations growing wild in Serbia in regards to biogeography and chemotaxonomy. Using GC/MS and GC/FID, seventeen n-alkane homologues (C19–C35) were identified. n-Hentriacontane (C31) was dominant in all populat...
Source: Biochemical Systematics and Ecology - Category: Biochemistry Source Type: research
Authors: Trujillo-Ochoa JL, Viera-Segura O, Fierro NA Abstract Hepatitis A virus (HAV) is the most common cause of acute viral hepatitis worldwide. The virus is mainly transmitted via the fecaloral route and, the incidence of infection is closely related to low socioeconomic conditions and poor sanitation. Mexico, previously categorized an area of high endemicity for HAV infection, is undergoing epidemiological transition. However, a limited number of HAV-related scientific reports regarding to virus burden is available. According to the local government health agency (Secretarla de Salud, SSA in Spanish), from 199...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Authors: Steinbrück K, Fernandes R Abstract Paracoccidioidomycosis is a systemic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis and is restricted to Latin America. It normally affects lungs, skin and lymph nodes. Abdominal organs are usually not involved. In rare cases paracoccidioidomycosis may simulate neoplasm. Herein we describe our experience with four cases of paracoccidioidomycosis mimicking cholangiocarcinoma. To the best of our knowledge, this is the largest case series on this subject produced in English. Paracoccidioidomycosis must be considered as a differential ...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Authors: Koizumi Y, Hirooka M, Tanaka T, Sunago K, Yukimoto A, Imai Y, Watanabe T, Ishihara T, Yoshida O, Yamamoto Y, Takeshita E, Ikeda Y, Abe M, Hiasa Y Abstract Schistosomiasis infection is a major cause of morbidity and mortality in endemic areas. Developed countries have declared that schistosomiasis has been eradicated; however, residents of these countries may travel and stay in endemic areas and the number of foreign travelers is increasing in the recent years. Thus, schistosomiasis is regarded as an imported infection. Ultrasonography and serum antibody titer tests are well established as diagnostic method...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
CONCLUSIONS.: The groupings of viral sequences show that the cases of canine rabies reported in Arequipa are the result of the expansion of canine rabies from the endemic region of Puno. PMID: 31116337 [PubMed - in process]
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Authors: Palomino-Lescano H, Segura-Chávez D, Quispe-Orozco D, Castro-Suarez S, De la Cruz W, Zapata-Luyo W, Delgado-Ríos J, Cam J, Alvarado-Morales M, Paredes-Carcasi L, Cornejo-Herrera I, Meza-Vega M Abstract Autoimmune encephalitis with antibodies against the N-methyl-D-aspartate receptor (anti-NMDAR) is a disorder mediated by antibodies against neural surface antigens, whose early diagnosis and timely treatment improve the prognosis of the disease. Four cases with the definitive diagnosis of autoimmune encephalitis by anti-NMDAR are presented, treated at the National Institute of Neurological Scie...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Publication date: Available online 22 May 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Seungeun Han, Charles Lubelczyk, Graham J. Hickling, Alexia A. Belperron, Linda K. Bockenstedt, Jean I. Tsao
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
This study was conducted to assess genetic diversity of Tp1 and Tp2 genes from T. parva isolates that are recognized by CD8 + T-cells in cattle and buffalo. The Tp1 and Tp2 genes are currently under evaluation as candidates for inclusion in a subunit vaccine. A total of 130 blood samples collected from cattle which do not interact with buffalo (98), cattle co-grazing with buffalo (19) and buffalo (13) in Mara, Mbeya, Morogoro, Tanga, and Coast regions in Tanzania were used in this study. Genomic DNA was extracted from the blood samples, Tp1 and Tp2 genes were amplified using nested PCR and the PCR products we...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 22 May 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Rahul Mahapatra, Luis A. Marcos, David Cohen, Asa W. Viccellio, Aaron Sasson, Jela Bandovic, Eric D. Spitzer, Audun Lier
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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