Effectiveness and Safety of Therapeutic Regimens for Elderly Patients with Acute Myeloid Leukemia: A Systematic Literature Review

Acute myeloid leukemia (AML) is the second most common leukemia among adults. Although the median age at diagnosis is 67 years, with approximately one-third of patients aged 75 years or older, limited treatment options exist for the elderly, who have 5-year survival rates of only 5%. A systematic review was conducted to examine effectiveness and safety outcomes of treatment regimens in elderly ( ≥60 years old) patients with AML.Published literature on the topic was scant, and the review included only 22 articles examining outcomes.

Source: Clinical Lymphoma, Myeloma and Leukemia - May 9, 2018 Category: Hematology Authors: Jill A. Bell, Aaron Galaznik, Rachel Huelin, Michael Stokes, Yelan Guo, Robert J. Fram, Douglas V. Faller Tags: Review Article Source Type: research