Evaluation of a Risk-guided Strategy for Empiric Carbapenem Use in Febrile Neutropenia
Fever during a neutropenic episode in patients receiving chemotherapy or immunosuppressive therapy is a medical emergency requiring prompt administration of empiric antimicrobial therapy. Existing guidelines for management of febrile neutropenia like that of the Infectious Diseases Society of America (IDSA) recommends that high risk patients be hospitalised and treated with intravenous antibiotic. Monotherapy is now preferred over combination antibiotics [1]. Piperacillin-tazobactam, carbapenems (meropenem or imipenem-cilastatin), and antipseudomonal cephalosporins (e.g.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Ai Leng Khoo, Ying Jiao Zhao, Monica Teng, Ding Ying, Jing Jin, Yen Lin Chee, Li Mei Poon, Siew Eng Lim, Liang Piu Koh, Wee Joo Chng, Boon Peng Lim, Li Yang Hsu, Louis Yi Ann Chai Source Type: research
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