Evaluation of a Risk-guided Strategy for Empiric Carbapenem Use in Febrile Neutropenia

Fever during a neutropenic episode in patients receiving chemotherapy or immunosuppressive therapy is a medical emergency requiring prompt administration of empiric antimicrobial therapy. Existing guidelines for management of febrile neutropenia like that of the Infectious Diseases Society of America (IDSA) recommends that high risk patients be hospitalised and treated with intravenous antibiotic. Monotherapy is now preferred over combination antibiotics [1]. Piperacillin-tazobactam, carbapenems (meropenem or imipenem-cilastatin), and antipseudomonal cephalosporins (e.g.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research