Unraveling the Mechanisms of Nitrofurantoin Resistance and Epidemiological Characteristics among Escherichia coli Clinical Isolates

Escherichia coli is one of the most common Gram-negative bacterial pathogens that cause uncomplicated urinary tract infections (UTIs) and opportunistic infections in immunodeficient hosts within both hospital and community settings [1-2]. Recently, the separation rate of multi-drug resistant E. coli clinical isolates shows an increasing trend and brings greater attention and distress to clinicians and infectious disease practitioners [3-4]. In addition, the lack of effective clinical treatments against multi-drug resistant E.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research