Does high intensity exercise affects irisin plasma levels in hemodialysis patients? A pilot study.

CONCLUSION: These data suggest that intense intradialytic strength exercise was unable to increase the circulating concentration of irisin in HD patients. Moreover, our data show that after one hour of dialysis session, irisin plasma levels may be reduced. PMID: 29738032 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research

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Authors: Ogunleye A, Akinbodewa AA, Adejumo OA, Oluwafemi TT, Akinfaderin DA Abstract Oxidative stress has been implicated in the pathogenesis, progression of chronic kidney disease (CKD) and development of cardiovascular complications. Hemodialysis (HD) has also been described to contribute significantly to oxidative stress in CKD patients, though reports are conflicting. Objective: We evaluated the effects of one session of HD on the antioxidant capacity and lipid peroxidation in CKD patients. Method: Thirty-six CKD patients requiring HD were recruited into this study. Participants were naïve to HD a...
Source: Ghana Medical Journal - Category: African Health Tags: Ghana Med J Source Type: research
Authors: Patel J, Bridgeman MB Abstract Etelcalcetide (Parsabiv) for hyperparathyroidism in adults with chronic kidney disease on hemodialysis. PMID: 30013296 [PubMed]
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
Abstract Melioidosis has a high case fatality rate and is more common in patients with chronic kidney disease. Some authors recommended trimethoprim/sulfamethoxazole (TMP/SMX) prophylaxis for all hemodialysis (HD) patients during the wet season in melioidosis-endemic regions. Historical data were reviewed to determine if TMP/SMX prophylaxis was warranted in the HD population of Far North Queensland, Australia. Between 1997 and 2017, there were 242 culture-confirmed cases of melioidosis in the region, three (1.2%) occurred in HD patients; all survived without intensive care support. During the study period, there w...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
"Why I Chose Hemodialysis Over Peritoneal Dialysis": An Opinion Survey Among In-Center Hemodialysis Patients. Perit Dial Int. 2018 Jul-Aug;38(4):305-308 Authors: Valson AT, Asad RA, Radhakrishnan RC, Sinha S, Jacob S, Varughese S, Tamilarasi V Abstract Peritoneal dialysis (PD) penetration in India remains low despite the huge chronic kidney disease burden and unmet need for renal replacement therapy (RRT). In order to understand the socioeconomic reasons that govern patients' preference for hemodialysis (HD), we carried out an opinion survey among prevalent in-center HD patients at our instit...
Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research
CONCLUSIONS: No difference in rates of acute kidney injury was detected before and after implementation of a colorectal enhanced recovery protocol. Independent predictors of acute kidney injury were identified and could be used to alter the protocol in high-risk patients. Future study is needed to determine whether protocol modifications will further decrease rates of acute kidney injury in this population. See Video Abstract at
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Socioeconomic Source Type: research
Some studies have shown abnormalities of nutritional status in patients with chronic kidney disease (CKD) [1,2]. Protein energy wasting (PEW) is highly prevalent in haemodialysis (HD) patients [3,4]. The underlying mechanisms of PEW are complex, but metabolic derangements related both to exaggerated protein degradation and decreased protein synthesis are of utmost importance [5,6,7,8]. Homeostasis between protein synthesis and degradation depends on protein intake and utilization. Accelerated protein degradation, without a sufficient protein supply, may lead to skeletal muscle wasting (9).
Source: Nutrition - Category: Nutrition Authors: Source Type: research
Publication date: Available online 18 May 2018Source: American Journal of Kidney DiseasesAuthor(s): Victoria Títoff, Heather N. Moury, Igor B. Títoff, Kevin M. KellyThere are 2 major categories of patients with seizures and chronic kidney disease (CKD): patients who develop acute symptomatic seizures in the setting of CKD and patients with epilepsy who at some point develop CKD. The incidence of uremic seizures with kidney failure is ∼10%. These seizures are often nonconvulsive and may mimic uremic encephalopathy. Recognition and management of such situations may be challenging for treating physicians who...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
In this study, we proposed a new approach to identify IBP patterns to classify ESRD patients. We used the dynamic time warping (DTW) algorithm to measure the similarity between two series of IBP data. Five blood pressure (BP) patterns were identified by applying the density peak clustering algorithm (DPCA) to the IBP data. To illustrate the association between BP patterns and prognosis, we constructed three random survival forest (RSF) models with different covariates. Model accuracy was improved 3.7–6.3% by the inclusion of BP patterns. The results suggest that BP patterns have critical clinical and prognostic signi...
Source: Journal of Biomedical Informatics - Category: Information Technology Source Type: research
ConclusionsHA was significantly associated with LVH. HA could be a novel biomarker of left ventricular overload, which is closely associated with an increased risk of death in HD patients.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
ConclusionOur study revealed that the risk of developing end stage renal diseases was increased among carriers of AA genotype for the rs10887800 polymorphism and GG genotype for the rs2576178 polymorphism.
Source: Egyptian Journal of Medical Human Genetics - Category: Genetics & Stem Cells Source Type: research
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