Promoter Free Allylation of Trichloroacetimidates with Allyltributylstannanes Under Thermal Conditions to Access the Common 1,1'-Diarylbutyl Pharmacophore

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB00687C, PaperNivedita S Mahajani, John D Chisholm 1,1'-Diarylbutyl groups are a common pharmacophore found in many biologically active small molecules. To access these systems under mild conditions, the reaction of diarylmethyl trichloroacetimidates with allyltributylstannanes was explored. Simply... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research