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Coaching to Up H2O Intake Does Not Slow eGFR Decline in CKD

WEDNESDAY, May 9, 2018 -- Coaching to increase water intake does not significantly slow the decline in kidney function among adults with chronic kidney disease, according to a study published in the May 8 issue of the Journal of the American Medical...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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In this issue of Journal of Neuro-Ophthalmology, M. Tariq Bhatti, MD and Mark L. Moster, MD will discuss the following 6 articles: Nazarian S, Hansford R, Rahsepar AA, Weltin V, McVeigh D, Gucuk Ipek E, Kwan A, Berger RD, Calkins H, Lardo AC, Kraut MA, Kamel IR, Zimmerman SL, Halperin HR. Safety of magnetic resonance imaging in patients with cardiac devices. N Engl J Med. 2017;377:2555–2564.Martin DR, Kalb B, Mittal A, Salman K, Vedantham S, Mittal PK. No incidence of nephrogenic systemic fibrosis after gadobenate dimeglumine administration in patients undergoing dialysis or those with severe chronic kidney disease....
Source: Journal of Neuro-Ophthalmology - Category: Opthalmology Tags: Literature Commentary: PDF Only Source Type: research
Source: CDC Preventing Chronic Disease - Category: International Medicine & Public Health Tags: Public Health Source Type: news
Conclusions Changes in renal biomarkers suggest mild acute kidney injury and reduced kidney function during a single bout of endurance cycling in the heat, without influence from moderate ibuprofen ingestion.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Source Type: research
Conditions:   Bone Disorder;   Chronic Kidney Diseases Intervention:   Other: Measure of etecalcetide on osteoclastic biology Sponsor:   Hospices Civils de Lyon Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In an interesting article, Dawidek et  al. reported that, in 92 adult patients with unilateral renal tumor, the optimal global renal function recovery occurred 6-12 weeks after minimally invasive partial nephrectomy. Global renal function “did not differ significantly from 1 year post-operatively”. Following surgery, nine patients (13%) developed de novo stage ≥3 chronic kidney disease (eGFR ≤60 ml/min/1.73m2) (1).
Source: Urology - Category: Urology & Nephrology Authors: Tags: Letters to the Editor Source Type: research
Coefficients of determination (R2) for continuous longitudinal data are typically reported as time-constant, if they are reported at all. The widely used mixed model with random intercepts and slopes yields the total outcome variance as a time-varying function. We propose a generalized and intuitive approach based on this variance function to estimate the time-varying predictive power (R2) of a variable on outcome levels and changes.
Source: Annals of Epidemiology - Category: Epidemiology Authors: Tags: Original article Source Type: research
In this study, we evaluated the effects of PrEP on urine levels of the following: α1-microglobulin (α1m), a marker of impaired tubular reabsorption; albuminuria, a measure of glomerular injury; and total proteinuria. Setting: The Iniciativa Profilaxis Pre-Exposicion (iPrEx) study randomized HIV-seronegative men and transgender women who have sex with men to oral TDF/FTC or placebo. The iPrEx open-label extension (iPrEx-OLE) study enrolled former PrEP trial participants to receive open-label TDF/FTC. Methods: A cross-sectional analysis compared urine biomarker levels by study arm in iPrEx (N = 100 treatmen...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Prevention Research Source Type: research
Authors: Caglayan V, Oner S, Onen E, Avci S, Aydos M, Kilic M, Demirbas M Abstract BACKGROUND: To evaluate success and complication rates of endourological stone treatments and to evaluate effects of percutaneous nephrolithotomy (PCNL) on renal functions, in patients with solitary kidneys. METHODS: In our center, 3150 patients underwent PCNL between 2003 and 2017 and 142 patients underwent retrograd intrarenal surgery (RIRS) between 2013 and 2017. We retrospectively analysed the data of 82 patients with solitary kidney who underwent PCNL and of 8 patients with solitary kidney who underwent RIRS. Complications w...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
We present a 42-year-old man with a BMI of 32, who was referred because of proteinuria and decreased renal function. We were impressed by his markedly muscular physique. A renal biopsy was performed, which showed focal segmental glomerular sclerosis (FSGS). Is this patient merely an obese person with FSGS or is something else going on here? We performed extensive clinical and laboratory examinations, genetic testing, and anthropometric data monitoring over time. We transferred our methodology for routine FSGS mutation screening (Sanger sequencing) to the Ion Torrent PGM platform with a new custom-targeted NGS gene panel (I...
Source: Case Reports in Nephrology and Dialysis - Category: Urology & Nephrology Source Type: research
Authors: Frisch NB, Wessell N, Charters M, Greenstein A, Shaw J, Peterson E, Trent Guthrie S Abstract The purpose of this study was to identify the specific risk factors that affect mortality in patients with hip fractures and differentiate mortality-associated factors between intertrochanteric (IT) and femoral neck (FN) fractures. A total of 1538 consecutive patients with hip fractures were treated at the authors' institution between January 2005 and October 2013. Ultimately 858 IT and 479 FN fracture patients were included on the basis of age>60 years with an isolated hip fracture. Mortality rate at 90 days wa...
Source: Journal of surgical orthopaedic advances - Category: Orthopaedics Tags: J Surg Orthop Adv Source Type: research
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