Radiosurgery alone is associated with favorable outcomes for brain metastases from small-cell lung cancer

Brain metastases (BM) are a common problem for patients with small-cell lung cancer (SCLC) [1]. Despite transitions to radiosurgery (SRS) alone for limited brain metastases (BM) in other histologies [2], whole brain radiation therapy (WBRT) remains the standard in SCLC regardless of the number of BM [3]. The continued acceptance of WBRT for limited and even solitary BM in SCLC may be driven by underlying concerns regarding the potential for diffuse CNS progression, as well as the historical role of prophylactic cranial irradiation (PCI) in the absence of identifiable BM.

Source: Lung Cancer - April 2, 2018 Category: Cancer & Oncology Authors: Tyler P. Robin, Bernard L. Jones, Arya Amini, Matthew Koshy, Laurie E. Gaspar, Arthur K. Liu, Sameer K. Nath, Brian D. Kavanagh, D. Ross Camidge, Chad G. Rusthoven Tags: Short communication Source Type: research