Facile Synthesis of 2,3-Benzodiazepines Using One-pot Two-step Phosphate-Assisted Acylation-Hydrazine Cyclization Reactions

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB00708J, PaperAkinari Sumita, Jinhee Lee, Yuko Otani, Tomohiko Ohwada Here, we report new methodology for synthesizing 2,3-benzodiazepines and their analogues by means of phosphate-assisted acylation reaction of 1-arylpropan-2-ones with a carboxylic acid followed by hydrazine cyclization in a one-pot... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research