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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Vasoinvasive Aspergillus infection in immunocompetent patients is rare and primarily encountered as a postoperative complication, such as aortitis, endocarditis, arterial thrombosis, or surgical site/endoprosthesis infection (1 –3). This brief report describes a case of acute left upper limb ischemia secondary to intra-arterial aspergillus thrombus resulting in early subclavian stent occlusion. Our institutional review board does not require approval for case reports.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Allergic bronchopulmonary aspergillosis is an immunologic pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus. This disorder is most commonly seen in patients with poorly controlled asthma and cystic fibrosis. It is rarely reported in chronic granulomatous disease patients; however, there are no cases reported with hematopoietic stem cell transplantation in the English literature. Herein, we report a patient with chronic granulomatous disease who had hematopoietic stem cell transplantation and subsequently developed allergic bronchopulmonary aspergillosis.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
ConclusionsThe results demonstrate the power of complementary transcriptomic and proteomic analyses in the study of pathogen defense and resistance in plants, and the chitinase could play an important role in the defense response of peanut to A. flavus. Current study also constitutes the first step towards building an integrated omics data platform for the development of Aspergillus-resistant peanut cultivars.
Source: Electronic Journal of Biotechnology - Category: Biotechnology Source Type: research
ConclusionThe inoculation of seeds with A. niger and Azotobacter may replace costly and environment toxic chemical fertilizers with environment friendly and cost effective biofertilizers.
Source: Biotechnology Reports - Category: Biotechnology Source Type: research
In this study, a natural antimicrobial cationic peptide of epsilon-poly-l-lysine (EPL) decorated ordered mesoporous silica (SBA-15) was facilely prepared for the efficient loading of antifungal itraconazole (ITZ) drugs. The characterized mesoporous SBA-15/EPL/ITZ composite exhibited remarkable antifungal performance against Aspergillus fumigatus as a model mold, which was attributed to synergistic antifungal activities of ITZ and EPL in the mesopores. Moreover, the in vitro release behaviors of ITZ in the composite nanoexcipients both in simulated gastric fluid and fasted state simulated intestinal fluid were studied. The ...
Source: Appl Human Sci - Category: Physiology Authors: Tags: Mater Sci Eng C Mater Biol Appl Source Type: research
Conclusion: The findings of this study showed that the extract prepared with the 50% acetone from Micromeria graeca has the highest phenolics content and revealed the best biological activities. So, this study has allowed us to find the suitable solvent for the preparation of the M. graeca extract for several uses.
Source: Current Nutrition and Food Science - Category: Nutrition Source Type: research
Authors: Frings DP, Simon M, Kluge S PMID: 30892194 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Publication date: Available online 20 March 2019Source: Biochemical Engineering JournalAuthor(s): Gordana Kovačević, Raluca Ostafe, Rainer Fischer, Radivoje ProdanovićAbstractGlucose oxidase (GOx) is a promising candidate for construction of implantable miniature biofuel cells and biosensors for continuous glucose monitoring. The main drawback that limits current application of GOx in these devices is its low stability, especially sensitivity to reactive oxygen species. In order to address this problem, we performed saturation mutagenesis at all 11 methionine residues as their interaction with reactive oxygen species in...
Source: Biochemical Engineering Journal - Category: Biochemistry Source Type: research
Authors: Ceylan B, Yilmaz M, Beköz HS, Ramadan S, Ertan Akan G, Mert A Abstract Invasive aspergillosis is a severe infection that generally involves the lungs. Primary gastrointestinal aspergillosis is the least common form of invasive aspergillosis. A patient aged 65 years developed a febrile neutropenic episode following an autologous stem cell transplant for plasmacytoid variant diffuse large B-cell gastric non-Hodgkin's lymphoma. He had abdominal pain on the second day of the febrile neutropenic episode and ileus occurred on the sixth day. His general condition deteriorated despite broad spectrum antibioti...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
BackgroundSolitary chemosensory cells (SCCs) are rare epithelial cells enriched in nasal polyps and are the primary source of interleukin ‐25 (IL‐25), an innate cytokine eliciting T‐helper 2 (Th2) immune response. Although it is proposed that SCCs are stimulated by antigens released by upper airway pathogens, the exogenous triggers of human SCCs remain elusive. We studied patients with noninvasive fungal rhinosinusitis to determ ine whether extracts ofAspergillus fumigatus andAlternaria alternata stimulate SCC proliferation as an early event in type 2 inflammation.MethodsMulticolor flow cytometry, immunofluorescence,...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
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