Fabrication and characterization of metal organic frameworks/ polyvinyl alcohol cryogel and their application in extraction of non-steroidal anti-inflammatory drugs in water samples.

Fabrication and characterization of metal organic frameworks/ polyvinyl alcohol cryogel and their application in extraction of non-steroidal anti-inflammatory drugs in water samples. Anal Chim Acta. 2018 Aug 31;1022:45-52 Authors: Wang Y, Zhang Y, Cui J, Li S, Yuan M, Wang T, Hu Q, Hou X Abstract A series of novel MOFs/PVA composite cryogel (MIL-101(Cr)/PVA, MIL-100(Fe)/PVA, ZIF-8(Zn)/PVA, MOF-199(Cu)/PVA and MIL-53(Al)/PVA) were fabricated by using a facile and green freeze-thaw approach for the first time. MIL-101(Cr)/PVA cryogel was selected as a VA-SPE sorbent for extraction of four NSAIDs in environmental water samples. The procedures of condition investigation (synthesis and extraction optimization) and characterization were also performed. And a satisfactory result of methodology validation was obtained by making use of HPLC-MS/MS. Under the optimum conditions, good sensitivity levels were achieved with the limits of detection between 0.007 and 0.037 μg L-1, a linearity of 0.10-10 μg L-1 for phenylbutazone, indomethacin, nimesulide and 0.020-2.0 μg L-1 for benorilate (r2 ≥ 0.9934). The relative recoveries of the target analytes were in the range from 78.44% to 105.7% with relative standard deviation (RSD) from 1.33% to 9.85%. In the extraction process, MIL-101(Cr)/PVA cryogel as a whole sheet outperformed the pristine dispersive MIL-101(Cr) in separation from solvent, and the application of cryogel also simpli...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research