Therapeutic Effect of HGF on NASH Mice Through HGF/c-Met and JAK2-STAT3 Signalling Pathway.

CONCLUSIONS: Excess HGF highly probable improved NASH liver function. Combined with its ligand, c-Met, HGF may promote the phosphorylation of JAK2-STAT3 and inhibit inflammation in NASH. Therefore, it may be potentially useful treatment for NASH.
PMID: 29735799 [PubMed - in process]

Source: Annals of Hepatology - May 9, 2018 Category: Gastroenterology Tags: Ann Hepatol Source Type: research