Association between Fas/FasL gene polymorphism and musculoskeletal degenerative diseases: a meta-analysis

It was reported that Fas (rs1800682, rs2234767) and FasL (rs5030772, rs763110) gene polymorphism might be related to the risk of musculoskeletal degenerative diseases (MSDD), such as osteoarthritis (OA), inter...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Research article Source Type: research

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Authors: Eftekharsadat B, Aghamohammadi D, Dolatkhah N, Hashemian M, Salami H Abstract Background: We aimed to determine dietary intake and serum concentration of α-tocopherol and lycopene in subjects with knee osteoarthritis (KOA) in relation to pain intensity and functional status and comparing them with healthy controls. Methods: This case-control study was conducted among 35 patients with primary KOA and 35 matched healthy subjects selected using convenience sampling method. Dietary intakes of alpha-tocopherol and lycopene were estimated from 24-hour dietary records. Visual Analogue Scale (VAS) and Weste...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
ConclusionsIn all probability, the left knee reflects a case of congenital ankylosis with a differential diagnosis of subadult trauma. The female’s skeleton had adapted to the impairment. Their risk is likely to have been elevated because of climatic and pandemic events during this period.SignificanceFirst reported case of congenital knee ankylosis.LimitationsThe left knee joint was damaged during excavation.Suggestions for further researchAdditional imaging is advised.
Source: International Journal of Paleopathology - Category: Pathology Source Type: research
AbstractOsteoarthritis (OA) is a chronic joint disease that leads to pain and functional incapacity. The aim of the study is to investigate the effects of the incorporation of photobiomodulation (PBM) (via cluster) into a physical exercise program on the level of pain, lower limb muscle strength, and physical capacity, in patients with knee OA. Sixty-two female volunteers with a diagnosis of knee OA were distributed in 4 groups: exercise associated with placebo PBM group, exercise associated with active PBM group, active PBM group, and placebo PBM group. Sixteen sessions of lower limb strength exercises and PBM via cluster...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Conclusions: Therapeutic exercises and playing AVGs similarly improved the pain of patients with knee OA; however, playing AVGs improved dynamic balance, physical functional performance, and physical health more than therapeutic exercises did.
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Conclusions: Tai Chi may be beneficial for improving balance and reducing falls in older people and those with Parkinson disease. Because of limitations and inconsistent conclusions, further rigorous, normative and comprehensive SRs are needed to provide robust evidence for definitive conclusions.
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
This report presents the case of a 40-year-old male snowboard instructor who suffered from a neglected fracture of the lateral process of the talus and was treated with open reduction using an iliac autogenous bone graft. Subsequently, partial resection of the anterior aspect of the process was required to treat the impingement syndrome that developed secondary to the united but enlarged lateral process. The patient resumed his activities a year after the second operation. We describe the consequences of misdiagnosis of the lateral process of the talus and its management.
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
DiscussionTrapeziectomy with LRTI for thumb carpometacarpal osteoarthritis provided early subjective improvements in outcomes as early as 3 months post-procedure. However, more than 6 months are required to determine objective improvements in outcomes. To obtain early patient-reported satisfactory outcomes, we should focus not on improving hand and finger strength, but on treating postoperative surgical site pain and preventing thumb stiffness.Level of evidenceIV, retrospective therapeutic study.
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
Condition:   Knee Osteoarthritis Interventions:   Procedure: Pulse Radiofrequency;   Procedure: Standard of Care Intra- Articular Injection;   Procedure: Placebo Intra-Articular Injection Sponsor:   Center For Interventional Pain and Spine Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Osteoarthritis;   Osteo Arthritis Knee;   Osteo Arthritis Shoulders;   Osteoarthritis of Multiple Joints;   Osteoarthritis, Hip;   Osteoarthritis - Ankle/Foot Interventions:   Procedure: Tissue Stromal Vascular Fraction (tSVF) Arm 1;   Biological: PRP Concentrate Arm 1;   Procedure: Tissue Stromal Vascular Fraction (tSVF) Arm 2;   Biological: PRP Concentrate Arm 2;   Procedure: Cellular Stromal Vascular Fraction (cSVF) Arm 2;   Procedure: Cellular Stromal Vascul...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: Statistically significant decreases in alpha angle were noted for both surgical techniques, with larger decreases seen in the anterior mini-open group. PMID: 31966967 [PubMed]
Source: World Journal of Orthopaedics - Category: Orthopaedics Tags: World J Orthop Source Type: research
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