Determination of gyrA and parC mutations and prevalence of plasmid-mediated quinolone resistance genes in Escherichia coli and Klebsiella pneumoniae isolated from patients with UTI in Iran
Conclusions FQ resistance was much more common in E. coli isolates than in K. pneumoniae. While mutations in drug target encoding genes gyrA and parC were the major mechanisms involved in FQ resistance in E. coli isolates, PMQR determinants commonly mediated resistance in K. pneumoniae isolates.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
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