Largest-ever global response to cholera targets 2 million people in Africa

The largest cholera vaccination drive in history targeting two million people across Africa is underway, the United Nations announced on Monday, in response to a series of recent deadly outbreaks of the water-borne disease.  
Source: UN News Centre - Health, Poverty, Food Security - Category: International Medicine & Public Health Source Type: news

Related Links:

AbstractPurpose of ReviewThis review describes the basic epidemiologic, clinical, and microbiologic aspects of cholera, highlights new developments within these areas, and presents strategies for applying currently available tools and knowledge more effectively.Recent FindingsFrom 1990 to 2016, the reported global burden of cholera fluctuated between 74,000 and 595,000 cases per year; however, modeling estimates suggest the real burden is between 1.3 and 4.0 million cases and 95,000 deaths yearly. In 2018, the World Health Assembly endorsed a new initiative to reduce cholera deaths by 90% and eliminate local cholera transm...
Source: Current Epidemiology Reports - Category: Epidemiology Source Type: research
[Guardian] Maiduguri -World Health Organisation (WHO) Representative in Nigeria, Dr. Wondimagegnehu Alemu, says the global agency in collaboration with the state government has taken a vaccination campaign to very prone councils in the wake of the recent cholera outbreak in Adamawa.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[Premium Times] In response to the cholera outbreak in Adamawa State, the World Health Organisation has began the first round of the two-phase oral vaccination (OCV).
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Authors: Abstract Oral rehydration was once the mainstay of treatment for cholera, but today's cholera outbreaks fuelled by conflict and instability require a new approach. Sophie Cousins reports. PMID: 29962546 [PubMed - in process]
Source: Bulletin of the World Health Organization - Category: International Medicine & Public Health Tags: Bull World Health Organ Source Type: research
ConclusionTo resolve this problem, there is a need for an oral cholera vaccine to be introduced. There is also a need to develop strategies and interventions relating to water, sanitation, and hygiene, to be initiated by the Ministry of Health, with component activities that are culturally tailored to Ghanaian communities. Policy change towards the prevention of outbreaks in Ghana is identified as another requisite.
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research
(Howard Hughes Medical Institute) A weakened version of the bacteria that causes cholera provides quick protection to rabbits. The vaccine may one day stop outbreaks of the deadly intestinal disease.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Outbreaks of cholera, a rapidly fatal diarrheal disease, often spread explosively. The efficacy of reactive vaccination campaigns—deploying Vibrio cholerae vaccines during epidemics—is partially limited by the time required for vaccine recipients to develop adaptive immunity. We created HaitiV, a live attenuated cholera vaccine candidate, by deleting diarrheagenic factors from a recent clinical isolate of V. cholerae and incorporating safeguards against vaccine reversion. We demonstrate that administration of HaitiV 24 hours before lethal challenge with wild-type V. cholerae reduced intestinal colonization by t...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
Abstract Problem: With limited global supplies of oral cholera vaccine, countries need to identify priority areas for vaccination while longer-term solutions, such as water and sanitation infrastructure, are being developed. Approach: In 2017, Malawi integrated oral cholera vaccine into its national cholera control plan. The process started with a desk review and analysis of previous surveillance and risk factor data. At a consultative meeting, researchers, national health and water officials and representatives from nongovernmental and international organizations reviewed the data and local epidemiological k...
Source: Bulletin of the World Health Organization - Category: International Medicine & Public Health Authors: Tags: Bull World Health Organ Source Type: research
This report covers the topics of pandemics, epidemics and partnerships, including regulatory convergence initiatives, new technologies and novel vaccines, discussed by leading public and private sector stakeholders at the 18th Annual General Meeting (AGM) of the Developing Countries Vaccine Manufacturers' Network (DCVMN). Contributions of Gavi and the vaccine industry from emerging countries to the growing global vaccine market, by improving the supply base from manufacturers in developing countries and contributing to 58% of doses, were highlighted. The Coalition for Epidemic Preparedness Innovations (CEPI), the Internati...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
k AJ, Brown TW, Derado G, Garrett N, Kim S, Hubbard S, Kahler AM, Malambo W, Mintz E, Murphy J, Narra R, Rao GG, Riggs MA, Weber N, Yard E, Zyambo KD, Bakyaita N, Monze N, Malama K, Mulwanda J, Mukonka VM Abstract On October 6, 2017, an outbreak of cholera was declared in Zambia after laboratory confirmation of Vibrio cholerae O1, biotype El Tor, serotype Ogawa, from stool specimens from two patients with acute watery diarrhea. The two patients had gone to a clinic in Lusaka, the capital city, on October 4. Cholera cases increased rapidly, from several hundred cases in early December 2017 to approximately 2,000 by...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
More News: African Health | Cholera | International Medicine & Public Health | Outbreaks | United Nations | Vaccines