Health Tip: Help Prevent E coli Infection
-- Escherichia coli(E. coli) is a bacterium that's found in the environment, foods and intestines of people and animals. Many strains are harmless, but some can make you very sick, causing diarrhea, urinary tract infection, respiratory illness and...
CONCLUSION: The vaccine has impact on the recurrent cystitis relapse rate. We suggest that more studies be carried out to evaluate the vaccine cost-benefit and its effectiveness in complicated urinary infections. PMID: 29790468 [PubMed - in process]
Conclusions: Ceftazidime–avibactam was very active against a large collection of Gram-negative bacilli isolated from pediatric patients, including P. aeruginosa and Enterobacteriaceae with an ESBL screening–positive phenotype and resistant to carbapenems.
CONCLUSION: Our study revealed multiple deficiencies in diagnosis, antibiotic choice, treatment duration, and reevaluation. PMID: 29747905 [PubMed - as supplied by publisher]
Conclusion An interplay of resistance mechanisms increased the level of resistance to FQs, and the high frequency of putative plasmid-mediated quinolone resistance genes associated with ESBL-producing isolates reduced therapeutic options to treat UTIs in the affected population.
Conclusions This study highlights the potential risk of spread of MCR-1-carrying, ESBL-producing E. coli in the community. The genome sequence of E. coli LX13 will facilitate the understanding of colistin resistance mechanisms and genomic features of clinically isolated colistin-resistant E. coli.
CONCLUSIONS: The male: female ratio for urinary tract infection was 3.3:1. Non-Escherichia coli etiologies should be considered in empirical treatment. Fever was the main symptom. Positive nitrite is highly suggestive of UTI but has low sensitivity; whereas pyuria ≥ 10,000/mL revealed good sensitivity, but low specificity. Peripheral white blood cell count and C-reactive protein concentration have limited usefulness to suggest UTI. PMID: 29738037 [PubMed - as supplied by publisher]
ConclusionsOur results suggest that the incidence of ESBL producers among CA-UTIs is high. Male gender, pediatrics, comorbidity and UTI in the previous 12 months were associated with a higher risk for infection. Continuous surveillance and prudent antibiotic use by healthcare professionals are important factors for effective control of ESBL associated infections.
Escherichia coli is one of the most common Gram-negative bacterial pathogens that cause uncomplicated urinary tract infections (UTIs) and opportunistic infections in immunodeficient hosts within both hospital and community settings [1-2]. Recently, the separation rate of multi-drug resistant E. coli clinical isolates shows an increasing trend and brings greater attention and distress to clinicians and infectious disease practitioners [3-4]. In addition, the lack of effective clinical treatments against multi-drug resistant E.
Conclusions FQ resistance was much more common in E. coli isolates than in K. pneumoniae. While mutations in drug target encoding genes gyrA and parC were the major mechanisms involved in FQ resistance in E. coli isolates, PMQR determinants commonly mediated resistance in K. pneumoniae isolates.
AbstractRaoultella ornithinolytica is a Gram-negative, non-motile, encapsulated, aerobic bacillus belonging to the Enterobacteriaceae family.R. ornithinolytica is a not very common, but emergent causal agent of human infection, and its expression of beta-lactamase provides resistance to commonly used antibiotics. The pathogenetic potential ofR. ornithinolytica isolates in human disease has become increasingly important. Several cases of hospital-acquired infection, mostly associated with invasive procedures, or in patients with co-morbidity caused byR. ornithinolytica, have been previously reported in the adult population....