Synthesis of pyridopyrimidinones by N-heterocyclic carbene palladium(II) supported on KCC-1 in aqueous solution

Publication date: Available online 5 May 2018 Source:Journal of Organometallic Chemistry Author(s): Seyed Mohsen Sadeghzadeh, Rahele Zhiani New N, N′-substituted imidazolium salts and their corresponding diiodopyridinepalladium (II) complexes were successfully synthesized and supported on KCC-1 (KCC-1/Pd-NHC-Py) has been developed for synthesis of pyridopyrimidinones, providing excellent yields of the corresponding products with remarkable chemoselectivity. This morphology ultimately leads to higher catalytic activity for the KCC-1-supported nanoparticles. The KCC-1/Pd-NHC-Py NPs were thoroughly characterized by using TEM, FESEM, TGA, and BET. We supported a drug on the surface of a silica and used as a catalyst for synthesis another drug. Graphical abstract
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research