Smoking and Death; Vessels for CABG: It's PodMed Double T! (with audio)

(MedPage Today) -- This week's topics include the best blood vessel for cardiac bypass grafts, rates of autism, five healthy lifestyle factors and their impact on mortality, and managing COPD
Source: MedPage Today Pulmonary - Category: Respiratory Medicine Source Type: news

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Authors: Oshagbemi OA, Franssen FME, van Kraaij S, Braeken DCW, Wouters EFM, Maitland-van der Zee AH, Driessen JHM, de Vries F Abstract Although recently introduced in the pharmacological treatment algorithm of chronic obstructive pulmonary disease (COPD), there is a need for more data supporting the use of blood eosinophil counts as a biomarker to guide inhaled corticosteroids (ICS) therapy. The aim of this study was to evaluate the risk of moderate and/or severe exacerbations and all-cause mortality in a large primary care population after withdrawal of ICS compared to continued users stratified by elevated blood...
Source: COPD: Journal of Chronic Obstructive Pulmonary Disease - Category: Respiratory Medicine Tags: COPD Source Type: research
Authors: Chabowski M, Juzwiszyn J, Bolanowska Z, Brzecka A, Jankowska-Polańska B Abstract Chronic nonmalignant pulmonary diseases impose a heavy burden on patients, generate health-care costs, and contribute to poor health-related quality of life. It has been found that a wide range of factors negatively affects quality of life, but the role of acceptance of illness needs to be further investigated. The aim of the study was to evaluate the relationship between acceptance of illness and quality of life in patients with chronic nonmalignant pulmonary diseases. The study encompassed 200 patients of the mean age 58&nb...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
ConclusionWe have used MSC-exo via intranasal administration to treat both BTBR and shank3 KO mice. The behavioral effect seemed 3 weeks post the treatment.The behavioral amelioration was seen in all the core symptoms including social interaction, repetitive behaviors, and vocal communication.
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionWe used gold nanoparticles loaded exosomes for in-vivo neuroimaging and present specific migration and homing to various brain pathologies including stroke, Parkinson's, Alzheimer's, Autism and healthy brains as a control. By this method, we visualized the migration and homing abilities of exosomes in long-term follow-up ad report that in pathological areas they home for more than 96 hours while in healthy brains they are being evacuated within 24 hours. Furthermore, we show that MSC-exo uses chemotaxis signaling to target the inflammatory areas in the brain.
Source: Cytotherapy - Category: Cytology Source Type: research
ConclusionStromal vascular fraction (SVF) therapy has been performed over the past seven years to treat 493 patients by our group in five clinical centers. SVF was isolated from the lipoaspirate collected from each respective patient through a simple manual liposuction procedure. For each patients, blood was drawn as well to isolate platelet-rich plasma (PRP). SVF and PRP were administered to all subjects by intravenous (IV) injection in an autologous manner, with minority group within the population received an additional spinal, intra-articular, or subcutaneous injections, or combination of several injection sites. The t...
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusion and Future Directions Above we reviewed a limited set of network medicine philosophies that seek to integrate biomedical big data to uncover meaningful biology. Network medicine approaches provide customized and optimized ways to leverage biomedical data. The choice of the appropriate network method is largely dictated by the underlying biological inquiry, hypotheses, study design, and available data. Although this review is not meant to be exhaustive, our intent was to give a essence of how biomedical data requires a nuanced approach when selecting network analyses and provide a resource for both network scien...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
In a blog post last week, I shared an excerpt from the new book that Paul Cerrato and I just completed,The Transformative Power of Mobile Medicine. Here is a second excerpt from Chapter 3,  “Exploring the Strengths and Weaknesses of Mobile Health Apps.”Even patients who are fully engaged in their own care still need access to medical apps they can trust. The IQVIA Institute for Human Data Science has performed a detailed analysis of the clinical evidence supporting mobile health apps, rating their maturity and relative quality. Its rating scale places a single observational study near the bottom of th...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
Authors: Grant WB Abstract Vitamin D, traditionally well known for its role in maintaining optimal health through its contribution to calcium metabolism and skeletal health, has received increased attention over the past two decades, with considerable focus being placed on its nonskeletal benefits. This paper is a narrative review of the nonskeletal health benefits of vitamin D, of particular interest to inhabitants of Mediterranean countries, namely, autism, cancer, cardiovascular disease, chronic obstructive pulmonary disease, dental caries, diabetes mellitus, erectile dysfunction, hypertension, metabolic syndrom...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
Conclusion: While the integrated, per capita, exposure of PM for a large fraction of the first-world may be less than 1 mg per day, links between several syndromes, including attention deficit hyperactivity disorder (ADHD), autism, loss of cognitive function, anxiety, asthma, chronic obstructive pulmonary disease (COPD), hypertension, stroke, and PM exposure have been suggested. This article reviews and summarizes such links reported in the literature.
Source: Journal of Occupational and Environmental Medicine - Category: Occupational Health Tags: Original Articles Source Type: research
Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 Address correspondence to F.P. Perera, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health, Columbia University Mailman School of Public Health, 722 West 168th St. ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentaries Children's Health February 2017 Source Type: research
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