DNA methylation-based reclassification of olfactory neuroblastoma

In conclusion, we demonstrate that institutionally diagnosed ONB are a heterogeneous group of tumors. Expression of cytokeratin, chromogranin A, the mutational status ofIDH2 as well as DNA methylation patterns may greatly aid in the precise classification of ONB.
Source: Acta Neuropathologica - Category: Neurology Source Type: research