Risk and Benefits of Bubble Continuous Positive Airway Pressure for Neonatal and Childhood Respiratory Diseases in Low- and Middle-Income Countries

Over 80% of the global burden of childhood deaths occur in Low ─ and Middle─Income Countries (LMIC). Of the leading causes of death, respiratory failure is common to the top three. Bubble Continuous Positive Airway Pressure (bCPAP) is a standard therapy considered safe and cost effective in high resource settings. Although high─quality trials from LMIC ar e few, pooled available trial data considered alongside studies from high─income countries suggests that bCPAP: (i) reduces mortality; (ii) reduces the need for mechanical ventilation; and (iii) prevents extubation failure.

Source: Paediatric Respiratory Reviews - May 4, 2018 Category: Respiratory Medicine Authors: Osayame A. Ekhaguere, Amsa B. Mairami, Haresh Kirpalani Source Type: research